Mitochondrial dynamics: overview of molecular mechanisms
L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
[HTML][HTML] Mitochondrial signalling and homeostasis: from cell biology to neurological disease
JJ Collier, M Oláhová, TG McWilliams… - Trends in …, 2023 - cell.com
Efforts to understand how mitochondrial dysfunction contributes to neurodegeneration have
primarily focussed on the role of mitochondria in neuronal energy metabolism. However …
primarily focussed on the role of mitochondria in neuronal energy metabolism. However …
[HTML][HTML] The rise of mitochondria in medicine
Once considered exclusively the cell's powerhouse, mitochondria are now recognized to
perform multiple essential functions beyond energy production, impacting most areas of cell …
perform multiple essential functions beyond energy production, impacting most areas of cell …
Disturbed mitochondrial dynamics and neurodegenerative disorders
Mitochondria form a highly interconnected tubular network throughout the cell via a dynamic
process, with mitochondrial segments fusing and breaking apart continuously. Strong …
process, with mitochondrial segments fusing and breaking apart continuously. Strong …
[HTML][HTML] Diagnosis and management of mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society
Purpose: The purpose of this statement is to review the literature regarding mitochondrial
disease and to provide recommendations for optimal diagnosis and treatment. This …
disease and to provide recommendations for optimal diagnosis and treatment. This …
[HTML][HTML] The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
Mitochondria are critical for metabolic homeostasis of the liver, and their dysfunction is a
major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a …
major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a …
[HTML][HTML] Mitochondrial quality control and muscle mass maintenance
V Romanello, M Sandri - Frontiers in physiology, 2016 - frontiersin.org
Loss of muscle mass and force occurs in many diseases such as disuse/inactivity, diabetes,
cancer, renal, and cardiac failure and in aging-sarcopenia. In these catabolic conditions the …
cancer, renal, and cardiac failure and in aging-sarcopenia. In these catabolic conditions the …
Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
AM Bertholet, T Delerue, AM Millet, MF Moulis… - Neurobiology of …, 2016 - Elsevier
Mitochondria are dynamic organelles that continually move, fuse and divide. The dynamic
balance of fusion and fission of mitochondria determines their morphology and allows their …
balance of fusion and fission of mitochondria determines their morphology and allows their …
Fusion and fission: interlinked processes critical for mitochondrial health
DC Chan - Annual review of genetics, 2012 - annualreviews.org
Mitochondria are dynamic organelles that continually undergo fusion and fission. These
opposing processes work in concert to maintain the shape, size, and number of …
opposing processes work in concert to maintain the shape, size, and number of …