Simple Summary Monoclonal antibodies are increasingly used for a broad range of
diseases. Rising demand must face with time time-consuming and laborious processes to …

Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or
eukaryotic superfamilies. Bovine pancreatic RNase A, bovine seminal BS-RNase, human …

The novel antibody-based immunotherapy in oncology exploits the activation of immune
system mediated by immunomodulatory antibodies specific for immune checkpoints. Among …

Monoclonal antibodies have been approved by the Food and Drug Administration for the
treatment of various human cancers. More recently, oligonucleotide aptamers have risen …

Advances in biomolecular technology have allowed the development of genetically fused
antibody–enzymes. Antibody–enzyme fusion proteins have been used to target tumors for …

Intracellular trafficking and subcellular deposition are critical factors influencing the
accumulation and posttranslational modifications of proteins. In seeds, these processes are …

With the advancement of biotechnology in the last two decades, optimized and novel
modalities and platforms of biologic moieties have emerged rapidly in drug discovery …

Background: ErbB2 is an attractive target for immunotherapy, as it is a tyrosine kinase
receptor overexpressed on tumour cells of different origin, with a key role in the development …

Pharmacokinetics and Toxicokinetics provides an overview of pharmacokinetics and
toxicokinetics in a comprehensible, interrelated, and applied manner. It integrates the …

The ErbB2 tyrosine kinase receptor is an attractive target for immunotherapy, as it is
overexpressed in many carcinomas. ImmunoRNases, made up of a human anti-ErbB2 scFv …