Psychological distress often causes suffering in terminally ill patients and their families and
poses challenges in diagnosis and treatment. Increased attention to diagnosis and treatment …

This structured review addresses the issue of whether antidepressants have an
antinociceptive (analgesic) effect for chronic pain independent of their antidepressant effect …

In the last 30 years antidepressant drugs have been used increasingly in the treatment of
patients with chronic pain. This article reviews the results of some 40 placebo-controlled …

This paper provides a systematic, evidence-based review of the psychological issues
confronted by patients at the end of life, drawing on recent literature. The epidemiology …

Depression is a prevalent psychiatric syndrome in the cancer population. We review the
spectrum of conditions in which depressive features are present, from normal responses to …

Objective. It has been hypothesized that serotonin reuptake inhibitor antidepressants (ADs)
are only weakly antinociceptive but augment noradrenergic (NA) antinociception. Thus, ADs …

Antidepressant agents have been suggested as treatments for functional gastrointestinal
syndromes since the early 1960s (1). Their efficacy has been demonstrated through …

The use of psychotropic drugs was studied in 200 cancer patients admitted to a medical
oncology unit at Memorial Sloan‐Kettering Cancer Center, New York, in December 1987 …

Pain is commonly present at the time of diagnosis of head and neck cancer. Pain occurs in
all patients treated for oropharyngeal cancer. This study examined the prevalence, severity …

The most common psychiatric complications in the cancer population are depression,
anxiety, and delirium. All are more likely to occur in the cancer patient who has pain. This …