[HTML][HTML] Maturation of the locomotor circuitry in children with cerebral palsy

G Cappellini, F Sylos-Labini, AH Dewolf… - … in Bioengineering and …, 2020 - frontiersin.org
The first years of life represent an important phase of maturation of the central nervous
system, processing of sensory information, posture control and acquisition of the locomotor …

A systematic review of neurogenesis in animal models of early brain damage: Implications for cerebral palsy

DB Visco, AE Toscano, PAR Juarez… - Experimental …, 2021 - Elsevier
Brain damage during early life is the main factor in the development of cerebral palsy (CP),
which is one of the leading neurodevelopmental disorders in childhood. Few studies …

Patch-based 3D U-Net and transfer learning for longitudinal piglet brain segmentation on MRI

P Coupeau, JB Fasquel, E Mazerand, P Menei… - Computer Methods and …, 2022 - Elsevier
Abstract Background and Objectives: In order to study neural plasticity in immature brain
following early brain lesion, large animal model are needed. Because of its morphological …

Mimicking partial to total placental insufficiency in a rabbit model of cerebral palsy

Z Shi, K Luo, S Jani, M February… - Journal of …, 2022 - Wiley Online Library
All placental abruptions begin as partial abruptions, which sometimes manifest as fetal
bradycardia. The progression from partial to total abruption was mimicked by a new rabbit …

[HTML][HTML] Trans-spinal direct current stimulation targets Ca2+ channels to induce persistent motor unit responses

W Song, JH Martin - Frontiers in Neuroscience, 2022 - frontiersin.org
Trans-spinal direct current stimulation (tsDCS) is a neuromodulatory approach to augment
spinal cord activity to improve function after neurological disease and injury. Little is known …

Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy

EJ Reedich, LT Genry, PR Steele… - The Journal of …, 2023 - Wiley Online Library
Cerebral palsy (CP) is caused by a variety of factors that damage the developing central
nervous system. Impaired motor control, including muscle stiffness and spasticity, is the …

Locomotion is impacted differently according to the perinatal brain injury model: Meta-analysis of preclinical studies with implications for cerebral palsy

S da Conceição Pereira, R Manhães-de-Castro… - Journal of Neuroscience …, 2021 - Elsevier
Background Different approaches to reproduce cerebral palsy (CP) in animals, contribute to
the knowledge of the pathophysiological mechanism of this disease and provide a basis for …

Inhibitory synaptic influences on developmental motor disorders

MJ Fogarty - International Journal of Molecular Sciences, 2023 - mdpi.com
During development, GABA and glycine play major trophic and synaptic roles in the
establishment of the neuromotor system. In this review, we summarise the formation …

[HTML][HTML] Muscle microbiopsy to delineate stem cell involvement in young patients: a novel approach for children with cerebral palsy

M Corvelyn, N De Beukelaer, R Duelen… - Frontiers in …, 2020 - frontiersin.org
Cerebral palsy (CP), the single largest cause of childhood physical disability, is
characterized firstly by a lesion in the immature brain, and secondly by musculoskeletal …

Beyond TORCH: A narrative review of the impact of antenatal and perinatal infections on the risk of disability

M Devaraju, A Li, S Ha, M Li, M Shivakumar, H Li… - Neuroscience & …, 2023 - Elsevier
Infections and inflammation during pregnancy or early life can alter child neurodevelopment
and increase the risk for structural brain abnormalities and mental health disorders. There is …