Inflammation at the crossroads of COVID-19, cognitive deficits and depression

NML e Silva, FGQ Barros-Aragão, FG De Felice… - …, 2022 - Elsevier
Acute neurological alterations have been associated with SARS-CoV-2 infection.
Additionally, it is becoming clear that coronavirus disease 2019 (COVID-19) survivors may …

[HTML][HTML] Mesenchymal stromal cell-derived secretome-based therapy for neurodegenerative diseases: overview of clinical trials

M Ghasemi, E Roshandel, M Mohammadian… - Stem cell research & …, 2023 - Springer
Background Over the past few years, mesenchymal stromal cells (MSCs) have attracted a
great deal of scientific attention owing to their promising results in the treatment of incurable …

[HTML][HTML] Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain …

L Porcher, S Bruckmeier, SD Burbano… - Journal of …, 2021 - Springer
Background Despite widespread acceptance that neuroinflammation contributes to age-
related cognitive decline, studies comparing protein expression of cytokines in the young …

[HTML][HTML] ADAM17-mediated shedding of inflammatory cytokines in hypertension

TM De Queiroz, N Lakkappa… - Frontiers in …, 2020 - frontiersin.org
The increase of Angiontesin-II (Ang-II), one of the key peptides of the renin-angiotensin
system (RAS), and its binding to the Ang-II type 1 receptor (AT 1 R) during hypertension is a …

[HTML][HTML] Alzheimer's disease animal models: elucidation of biomarkers and therapeutic approaches for cognitive impairment

T Nakai, K Yamada, H Mizoguchi - International journal of molecular …, 2021 - mdpi.com
Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder. It
is widely accepted that AD is mainly caused by the accumulation of extracellular amyloid β …

[HTML][HTML] The neuroprotective effect of short chain fatty acids against sepsis-associated encephalopathy in mice

J Liu, Y Jin, Y Ye, Y Tang, S Dai, M Li, G Zhao… - Frontiers in …, 2021 - frontiersin.org
Short chain fatty acids (SCFAs) are known to be actively involved in multiple brain disorders,
but their roles in sepsis-associated encephalopathy (SAE) remain unclear. Here, we …

[HTML][HTML] Autoimmune Neuroinflammatory Diseases: Role of Interleukins

AW Khan, M Farooq, MJ Hwang, M Haseeb… - International Journal of …, 2023 - mdpi.com
Autoimmune neuroinflammatory diseases are a group of disorders resulting from abnormal
immune responses in the nervous system, causing inflammation and tissue damage. The …

Levels of soluble interleukin 6 receptor and Asp358Ala are associated with cognitive performance and Alzheimer disease biomarkers

D Quillen, TM Hughes, S Craft, T Howard… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Alzheimer disease (AD) is a neurodegenerative disease
process manifesting clinically with cognitive impairment and dementia. AD pathology is …

Loss of SST and PV positive interneurons in the ventral hippocampus results in anxiety-like behavior in 5xFAD mice

H Li, J Zhao, L Lai, Y Xia, C Wan, S Wei, J Liang… - Neurobiology of …, 2022 - Elsevier
Neuropsychiatric symptoms, such as anxiety and depression often appear early in patients
with Alzheimer's disease (AD), and a comorbid, anxiety-like phenotype is also found in …

[HTML][HTML] New insight into neurological degeneration: Inflammatory cytokines and blood–brain barrier

J Yang, M Ran, H Li, Y Lin, K Ma, Y Yang… - Frontiers in Molecular …, 2022 - frontiersin.org
Neurological degeneration after neuroinflammation, such as that resulting from Alzheimer's
disease (AD), stroke, multiple sclerosis (MS) and post-traumatic brain injury (TBI), is typically …