[HTML][HTML] Bioaccumulation and in vivo fate of toxic benzylalkyldimethylammonium chloride in rats via the radiotracer analysis

JE Park, SH Ryu, S Ito, MK Song, EJ Gu, H Shin… - Chemosphere, 2023 - Elsevier
Benzylalkyldimethylammonium chloride (BAC), a quaternary ammonium compound (QAC),
is utilized in industrial and biomedical applications for antimicrobial purposes. Since the …

[HTML][HTML] Biodistribution and respiratory toxicity of chloromethylisothiazolinone/methylisothiazolinone following intranasal and intratracheal administration

MK Song, JE Park, SH Ryu, YW Baek, YH Kim… - Environment …, 2022 - Elsevier
A variety of isothiazolinone-containing small molecules have been registered and used as
chemical additives in many household products. However, their biodistribution and potential …

Quantitative PET tracking of intra-articularly administered 89Zr-peptide-decorated nanoemulsions

S Díez-Villares, L García-Varela… - Journal of Controlled …, 2023 - Elsevier
Intra-articular (IA) administration of drugs for the treatment of diseases such as rheumatoid
arthritis, osteoarthritis and psoriatic arthritis is a common strategy; however, the rapid …

New Long-Acting [89Zr]Zr-DFO GLP-1 PET Tracers with Increased Molar Activity and Reduced Kidney Accumulation

J Wilbs, R Raavé, M Boswinkel, T Glendorf… - Journal of Medicinal …, 2023 - ACS Publications
Positron emission tomography (PET) imaging is used in drug development to noninvasively
measure biodistribution and receptor occupancy. Ideally, PET tracers retain target binding …