Early life is a dynamic period for skin microbial colonization and immune development. We
postulate that microbial exposures in this period durably alter the skin immune trajectory and …

Our skin is the interface through which we mediate lifelong interactions with our surrounding
environment. Initial development of the skin's epidermis, adnexal structures, and barrier …

Breach of the skin barrier and subsequent wound healing occur in the context of microbial
communities of bacteria, fungi, and viruses. These polymicrobial communities are dynamic …

The US National Institute of Allergy and Infectious Diseases hosted a two-day virtual
workshop on skin microbial communities and their interactions with the host immune system …

Two major arms of skin ageing are changes in the skin's biophysical conditions and
alterations in the skin microbiome. This work partitioned both arms to study their interaction …

Atopic dermatitis (AD) is a common, chronic and relapsing inflammatory skin disease with
various clinical presentations and combinations of symptoms. The pathophysiology of AD is …

Mounting evidence indicates that the microbiota, the unique combination of micro-organisms
residing in a specific environment, plays an essential role in the development of a wide …

Background Atopic dermatitis (AD) patients display an altered skin microbiome which may
not only be an indicator but also a driver of inflammation. We aimed to investigate …

The interplay between the microbes and the skin barrier holds pivotal significance in skin
health and aging. The skin and gut, both of which are critical immune and neuroendocrine …

For decades research has centered on identifying the ideal balanced skin microbiome that
prevents disease and on developing therapeutics to foster this balance. However, this single …