Stem/stromal cells for treatment of kidney injuries with focus on preclinical models
A Torres Crigna, C Daniele, C Gamez… - Frontiers in …, 2018 - frontiersin.org
Within the last years, the use of stem cells (embryonic, induced pluripotent stem cells, or
hematopoietic stem cells), Progenitor cells (eg, endothelial progenitor cells), and most …
hematopoietic stem cells), Progenitor cells (eg, endothelial progenitor cells), and most …
Recent updates on mesenchymal stem cell based therapy for acute renal failure
A Missoum - Current urology, 2020 - karger.com
Acute kidney injury, formerly known as acute renal failure, is a pathological condition in
which ischemia or toxic damage contributes to the loss of renal proximal tubule epithelial …
which ischemia or toxic damage contributes to the loss of renal proximal tubule epithelial …
Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy
WC Tseng, PY Lee, MT Tsai, FP Chang… - Stem Cell Research & …, 2021 - Springer
Background Acute kidney injury (AKI) is an emerging global healthcare issue without
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL …
Y Zhang, X Qin, Y Yang, J Li, X Li, X Zou, Z Huang… - Phytomedicine, 2023 - Elsevier
Background Activation of renal fibroblasts into myofibroblasts plays an important role in
promoting renal interstitial fibrosis (RIF). Ginkgo biloba extract (EGb) can alleviate RIF …
promoting renal interstitial fibrosis (RIF). Ginkgo biloba extract (EGb) can alleviate RIF …
Ginkgobiloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial …
C Wei, Y Zhang, X Zhong, S Lu, X Zou, Y Yang… - Chinese Medicine, 2022 - Springer
Background Our previous study indicated that Ginkgo biloba leaf extract (EGb) could protect
against cisplatin-induced acute kidney injury in rabbits. The present study aimed to …
against cisplatin-induced acute kidney injury in rabbits. The present study aimed to …
(Mesenchymal) stem cell‐based therapy in cisplatin‐induced acute kidney injury animal model: Risk of immunogenicity and tumorigenicity
Ž Večerić-Haler, A Cerar, M Perše - Stem Cells International, 2017 - Wiley Online Library
Pathogenesis of AKI is complex and involves both local events in the kidney as well as
systemic effects in the body that are interconnected and interdependent. Despite intensive …
systemic effects in the body that are interconnected and interdependent. Despite intensive …
Mesenchymal stem cells therapy for acute kidney injury: a systematic review with meta-analysis based on rat model
P Wanyan, X Wang, N Li, Y Huang, Y She… - Frontiers in …, 2023 - frontiersin.org
Objective: To systematically evaluate the efficacy of mesenchymal stem cells (MSCs) for
acute kidney injury (AKI) in preclinical studies and to explore the optimal transplantation …
acute kidney injury (AKI) in preclinical studies and to explore the optimal transplantation …
Retinoic acid potentiates the therapeutic efficiency of bone marrow-derived mesenchymal stem cells (BM-MSCs) against cisplatin-induced hepatotoxicity in rats
MM Azzam, AM Hussein, BH Marghani… - Scientia …, 2022 - mdpi.com
(1) Background: Hepatotoxicity is a common health problem, and oxidative stress plays a
crucial role in its underlying mechanisms. We inspected the possible effect of retinoic acid …
crucial role in its underlying mechanisms. We inspected the possible effect of retinoic acid …
Does the route matter? A preclinical review of mesenchymal stromal cell delivery to the kidney
JC Kresse, E Gregersen, JCL Atay, M Eijken… - Apmis, 2023 - Wiley Online Library
Mesenchymal stromal/stem cell (MSC) therapy has been thoroughly tested in preclinical
animal models and holds great promise for the treatment of kidney diseases. It is becoming …
animal models and holds great promise for the treatment of kidney diseases. It is becoming …
Administration of mesenchymal stem cells in diabetic kidney disease: mechanisms, signaling pathways, and preclinical evidence
Y Zhu, M Luo, X Bai, Y Lou, P Nie, S Jiang, J Li… - Molecular and Cellular …, 2022 - Springer
Diabetic kidney disease (DKD) is a serious microvascular complication of diabetes.
Currently, the prevalence and mortality of DKD are increasing annually. However, with no …
Currently, the prevalence and mortality of DKD are increasing annually. However, with no …