Clinical and translational values of spatial transcriptomics
L Zhang, D Chen, D Song, X Liu, Y Zhang… - … and Targeted Therapy, 2022 - nature.com
The combination of spatial transcriptomics (ST) and single cell RNA sequencing (scRNA-
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …
Coronaviruses pathogenesis, comorbidities and multi-organ damage–A review
K Renu, PL Prasanna, AV Gopalakrishnan - Life sciences, 2020 - Elsevier
Abstract Human coronaviruses, especially COVID-19, is an emerging pandemic infectious
disease with high morbidity and mortality. Coronaviruses are associated with comorbidities …
disease with high morbidity and mortality. Coronaviruses are associated with comorbidities …
Fe-curcumin nanozyme-mediated reactive oxygen species scavenging and anti-inflammation for acute lung injury
R Yuan, Y Li, S Han, X Chen, J Chen, J He… - ACS central …, 2021 - ACS Publications
Pneumonia, such as acute lung injury (ALI), has been a type of lethal disease that is
generally caused by uncontrolled inflammatory response and excessive generation of …
generally caused by uncontrolled inflammatory response and excessive generation of …
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Patients diagnosed with coronavirus disease 2019 (COVID-19) become critically ill primarily
around the time of activation of the adaptive immune response. Here, we provide evidence …
around the time of activation of the adaptive immune response. Here, we provide evidence …
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
N-acetylcysteine to combat COVID-19: an evidence review
Z Shi, CA Puyo - Therapeutics and clinical risk management, 2020 - Taylor & Francis
The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known
for inducing multisystem organ dysfunction associated with significant morbidity and …
for inducing multisystem organ dysfunction associated with significant morbidity and …
Insulin resistance in COVID-19 and diabetes
Background The epidemiology of COVID-19 and its association with cardiometabolic
disorders is poorly understood. This is a narrative review that investigates the effects of …
disorders is poorly understood. This is a narrative review that investigates the effects of …
[HTML][HTML] Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design
Q Qiao, X Liu, T Yang, K Cui, L Kong, C Yang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …
and destruction of the lung air–blood barrier, leading to irreversible and substantial …
DPP4 and ACE2 in diabetes and COVID-19: therapeutic targets for cardiovascular complications?
I Valencia, C Peiro, O Lorenzo… - Frontiers in …, 2020 - frontiersin.org
COVID-19 outbreak, caused by severe acute respiratory syndrome (SARS)-CoV-2
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
[HTML][HTML] Diabetes mellitus and COVID-19: understanding the association in light of current evidence
S Sen, R Chakraborty, P Kalita… - World journal of clinical …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have posed a
problematic healthcare situation worldwide since December 2019. Diabetes mellitus is …
problematic healthcare situation worldwide since December 2019. Diabetes mellitus is …