Drug-drug interactions (DDIs) are one of the commonest causes of medication error in
developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20 …

The pharmacokinetics of methadone varies greatly from person to person; so, after the
administration of the same dose, considerably different concentrations are obtained in …

Drug-drug interactions have become an important issue in health care. It is now realized that
many drug-drug interactions can be explained by alterations in the metabolic enzymes that …

Minor cardiovascular adverse effects from antipsychotic drugs are extremely common. They
include effects such as postural hypotension and tachycardia due to anticholinergic or α 1 …

Clozapine has been found to be superior to traditional neuroleptics in the treatment of
refractory schizophrenia and is increasingly being used to treat schizophrenia, affective …

Methadone, an opioid analgesic, is used clinically in pain therapy as well as for substitution
therapy in opioid addiction. It has a large interindividual variability in response and a narrow …

The psychostimulants methylphenidate, amphetamine and pemoline are among the most
common medications used today in child and adolescent psychiatry for the treatment of …

Psychotherapeutic drugs (antipsychotics and antidepressants) are widely used for treating
anxiety. Many psychotherapeutic drugs are metabolized mainly by cytochrome P450 (CYP) …

Chronic kidney disease (CKD) is a long-term condition characterized by a gradual loss of
kidney functions, usually accompanied by other comorbidities including cardiovascular …

The dental team plays an integral role in safeguarding the general health of patients. Dental
health care workers should be able to recognize risk factors associated with hypertension …