Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
XL Fan, Y Zhang, X Li, QL Fu - Cellular and molecular life sciences, 2020 - Springer
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain
M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …
related to learning and memory. The expression of BDNF is highly regulated, and can lead …
Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke
Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …
essential roles in maintaining normal brain function, as they are a critical structural and …
Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
OBJECT Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …
Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves …
Y Zhang, M Chopp, ZG Zhang, M Katakowski… - Neurochemistry …, 2017 - Elsevier
Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve
functional outcome after experimental traumatic brain injury (TBI). The present study was …
functional outcome after experimental traumatic brain injury (TBI). The present study was …
Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells
M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …
Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge
The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It
acts as a highly biocompatible natural scaffold and as a source of several types of stem cells …
acts as a highly biocompatible natural scaffold and as a source of several types of stem cells …
Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities
Y Xiong, A Mahmood, M Chopp - Chinese Journal of Traumatology, 2018 - mednexus.org
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …