Biofuel metabolic engineering with biosensors
Highlights•Biosensors and their use in biofuel-related metabolic engineering are
introduced.•The pros and cons of major biosensor classes are reviewed.•Biosensors enable …
introduced.•The pros and cons of major biosensor classes are reviewed.•Biosensors enable …
Steps towards 'drop-in'biofuels: focusing on metabolic pathways
Highlights•Four major metabolic pathways that lead to biofuel production are reviewed.•The
production of branched-chain fatty acid improved biofuel cold-flow properties.•Non …
production of branched-chain fatty acid improved biofuel cold-flow properties.•Non …
Enhancing fatty acid production in Escherichia coli by Vitreoscilla hemoglobin overexpression
Our recent 13C‐metabolic flux analysis (13C‐MFA) study indicates that energy metabolism
becomes a rate‐limiting factor for fatty acid overproduction in E. coli strains (after “Push‐Pull …
becomes a rate‐limiting factor for fatty acid overproduction in E. coli strains (after “Push‐Pull …
Transcription factor-based biosensor: A molecular-guided approach for advanced biofuel synthesis
As a sustainable and renewable alternative to petroleum fuels, advanced biofuels shoulder
the responsibility of energy saving, emission reduction and environmental protection …
the responsibility of energy saving, emission reduction and environmental protection …
[HTML][HTML] Control strategies to manage trade-offs during microbial production
Highlights•Feedback control can mitigate the impact of the ribosomal cost.•Feedback control
alleviates metabolic burden caused by engineered metabolic pathways.•Metabolic switch …
alleviates metabolic burden caused by engineered metabolic pathways.•Metabolic switch …
A Förster Resonance Energy Transfer‐Based Ratiometric Sensor with the Allosteric Transcription Factor TetR
A recent description of an antibody‐free assay is significantly extended for small molecule
analytes using allosteric transcription factors (aTFs) and Förster resonance energy transfer …
analytes using allosteric transcription factors (aTFs) and Förster resonance energy transfer …
Engineering Escherichia coli to increase triacetic acid lactone (TAL) production using an optimized TAL sensor-reporter system
Abstract Triacetic acid lactone (TAL)(4-hydroxy-6-methyl-2-pyrone) can be upgraded into a
variety of higher-value products, and has potential to be developed into a renewable …
variety of higher-value products, and has potential to be developed into a renewable …
[HTML][HTML] 微生物细胞工厂的代谢调控
刘洋, 牟庆璇, 石雅南, 于波 - 生物工程学报, 2021 - cjb.ijournals.cn
代谢调控是构建微生物细胞工厂的重要技术手段. 随着合成生物学技术的不断突破,
挖掘和人工设计的高质量调控元件大幅度提升了对细胞代谢网络的改造能力; …
挖掘和人工设计的高质量调控元件大幅度提升了对细胞代谢网络的改造能力; …
Learning from quantitative data to understand central carbon metabolism
Quantitative analysis of metabolism has been used to identify driver reactions occurring
during cancer development and bottleneck reactions in the metabolic engineering of …
during cancer development and bottleneck reactions in the metabolic engineering of …
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli
E Kalkreuter, AM Keeler, AA Malico… - ACS synthetic …, 2019 - ACS Publications
The scaffolds of polyketides are constructed via assembly of extender units based on
malonyl-CoA and its derivatives that are substituted at the C2-position with diverse chemical …
malonyl-CoA and its derivatives that are substituted at the C2-position with diverse chemical …