The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

Lipid metabolism disorders are the primary causes for the occurrence and progression of
various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty …

Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …

Excessive alcohol consumption is a global healthcare problem. The liver sustains the
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …

Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …

Background & Aims Defects in lysosome function and autophagy contribute to the
pathogenesis of alcoholic liver disease. We investigated the mechanisms by which alcohol …

Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …

Chronic alcohol consumption is linked to the development of alcohol-associated liver
disease (ALD). This disease is characterized by a clinical spectrum ranging from steatosis to …