[PDF][PDF] Barrier to autointegration factor 1, procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase 3, and splicing factor 3b subunit 4 as early‐stage cancer decision markers …
An accurate tool enabling early diagnosis of hepatocellular carcinoma (HCC) is clinically
important, given that early detection of HCC markedly improves survival. We aimed to …
important, given that early detection of HCC markedly improves survival. We aimed to …
[HTML][HTML] Natural compounds: a potential treatment for alcoholic liver disease?
J Yan, Y Nie, M Luo, Z Chen, B He - Frontiers in pharmacology, 2021 - frontiersin.org
Excessive alcohol intake is a direct cause of alcoholic liver disease (ALD). ALD usually
manifests as fatty liver in the initial stage and then develops into alcoholic hepatitis (ASH) …
manifests as fatty liver in the initial stage and then develops into alcoholic hepatitis (ASH) …
[HTML][HTML] Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Abbreviations: ABCA1, ATP binding cassette subfamily A member; AH, alcohol‐associated
hepatitis; ALD, alcohol‐associated liver disease; BMDM, bone marrow–derived …
hepatitis; ALD, alcohol‐associated liver disease; BMDM, bone marrow–derived …
[HTML][HTML] PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease
Alcoholic liver disease (ALD) causes significant morbidity and mortality, and
pharmacological treatment options are limited. In this study, we evaluated the PCSK9 …
pharmacological treatment options are limited. In this study, we evaluated the PCSK9 …
[HTML][HTML] Mitochondrial DNA–enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
Over the last several years, one of the major advances in the field of alcoholic liver disease
research was the discovery that binge alcohol consumption induced neutrophilia and …
research was the discovery that binge alcohol consumption induced neutrophilia and …
Hepatoprotective effects of garlic against ethanol-induced liver injury: A mini-review
MJ Guan, N Zhao, KQ Xie, T Zeng - Food and Chemical Toxicology, 2018 - Elsevier
Alcoholic liver disease (ALD) is a progressively aggravated liver disease with a diverse
spectrum from steatosis to hepatitis, fibrosis, and cirrhosis. Epidemiological studies reveal …
spectrum from steatosis to hepatitis, fibrosis, and cirrhosis. Epidemiological studies reveal …
Diallyl disulfide suppresses the lipopolysaccharide-driven inflammatory response of macrophages by activating the Nrf2 pathway
XN Zhang, N Zhao, FF Guo, YR Wang, SX Liu… - Food and Chemical …, 2022 - Elsevier
Lipopolysaccharide (LPS)-driven activation of Kupffer cells plays critical roles in the
development of alcoholic liver disease (ALD). Accumulating evidence has revealed that …
development of alcoholic liver disease (ALD). Accumulating evidence has revealed that …
[HTML][HTML] Central role of intestinal epithelial glucocorticoid receptor in alcohol‐and corticosterone‐induced gut permeability and systemic response
Corticosterone, the stress hormone, exacerbates alcohol‐associated tissue injury, but the
mechanism involved is unknown. We examined the role of the glucocorticoid receptor (GR) …
mechanism involved is unknown. We examined the role of the glucocorticoid receptor (GR) …
[HTML][HTML] O-GlcNAc transferase suppresses necroptosis and liver fibrosis
Worldwide, over a billion people suffer from chronic liver diseases, which often lead to
fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no …
fibrosis and then cirrhosis. Treatments for fibrosis remain experimental, in part because no …
[HTML][HTML] Differential role of MLKL in alcohol-associated and non–alcohol-associated fatty liver diseases in mice and humans
T Miyata, X Wu, X Fan, E Huang, C Sanz-Garcia… - JCI insight, 2021 - ncbi.nlm.nih.gov
Hepatocellular death contributes to progression of alcohol–associated (ALD-associated)
and non–alcohol-associated (NAFL/NASH) liver diseases. However, receptor-interaction …
and non–alcohol-associated (NAFL/NASH) liver diseases. However, receptor-interaction …