[HTML][HTML] Natural products, PGC-1α, and Duchenne muscular dystrophy
Peroxisome proliferator-activated receptor γ (PPARγ) is a transcriptional coactivator that
binds to a diverse range of transcription factors. PPARγ coactivator 1 (PGC-1) coactivators …
binds to a diverse range of transcription factors. PPARγ coactivator 1 (PGC-1) coactivators …
[HTML][HTML] Dystrophin expression in myofibers of Duchenne muscular dystrophy patients following intramuscular injections of normal myogenic cells
D Skuk, B Roy, M Goulet, P Chapdelaine… - Molecular Therapy, 2004 - cell.com
Three Duchenne muscular dystrophy (DMD) patients received injections of myogenic cells
obtained from skeletal muscle biopsies of normal donors. The cells (30× 10 6) were injected …
obtained from skeletal muscle biopsies of normal donors. The cells (30× 10 6) were injected …
Imaging survival and function of transplanted cardiac resident stem cells
Objectives: The goal of this study is to characterize resident cardiac stem cells (CSCs) and
investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods …
investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods …
[HTML][HTML] DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model
CI Berul, CT Maguire, MJ Aronovitz… - The Journal of …, 1999 - Am Soc Clin Investig
Myotonic dystrophy (DM) is the most common form of muscular dystrophy and is caused by
expansion of a CTG trinucleotide repeat on human chromosome 19. Patients with DM …
expansion of a CTG trinucleotide repeat on human chromosome 19. Patients with DM …
[HTML][HTML] Current understanding of molecular pathology and treatment of cardiomyopathy in duchenne muscular dystrophy
TLE Van Westering, CA Betts, MJA Wood - Molecules, 2015 - mdpi.com
Duchenne muscular dystrophy (DMD) is a genetic muscle disorder caused by mutations in
the Dmd gene resulting in the loss of the protein dystrophin. Patients do not only experience …
the Dmd gene resulting in the loss of the protein dystrophin. Patients do not only experience …
Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector.
SK Tripathy, EC Svensson, HB Black… - Proceedings of the …, 1996 - National Acad Sciences
Erythropoietin (Epo)-responsive anemia is a common and debilitating complication of
chronic renal failure and human immunodeficiency virus infection. Current therapy for this …
chronic renal failure and human immunodeficiency virus infection. Current therapy for this …
Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy
JN Robinson-Hamm, CA Gersbach - Human genetics, 2016 - Springer
Duchenne muscular dystrophy is one of the most common inherited genetic diseases and is
caused by mutations to the DMD gene that encodes the dystrophin protein. Recent …
caused by mutations to the DMD gene that encodes the dystrophin protein. Recent …
Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration
Severe injury to the skeletal muscle often results in the formation of scar tissue, leading to a
decline in functional performance. Traditionally, tissue engineering strategies for muscle …
decline in functional performance. Traditionally, tissue engineering strategies for muscle …
The muscular dystrophies: from genes to therapies
RM Lovering, NC Porter, RJ Bloch - Physical therapy, 2005 - academic.oup.com
The genetic basis of many muscular disorders, including many of the more common
muscular dystrophies, is now known. Clinically, the recent genetic advances have improved …
muscular dystrophies, is now known. Clinically, the recent genetic advances have improved …
Reliability of hand‐held dynamometry in spinal muscular atrophy
We have assessed the reliability of hand‐held myometry in 33 patients with spinal muscular
atrophy (SMA), testing elbow flexion, handgrip, three‐point pinch, knee flexion, knee …
atrophy (SMA), testing elbow flexion, handgrip, three‐point pinch, knee flexion, knee …