Metabolism of dietary and microbial vitamin B family in the regulation of host immunity

K Yoshii, K Hosomi, K Sawane, J Kunisawa - Frontiers in nutrition, 2019 - frontiersin.org
Vitamins are micronutrients that have physiological effects on various biological responses,
including host immunity. Therefore, vitamin deficiency leads to increased risk of developing …

Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application

G Gyimesi, J Pujol-Giménez, Y Kanai… - Pflügers Archiv-European …, 2020 - Springer
Sodium glucose transporters (SGLTs) belong to the mammalian solute carrier family SLC5.
This family includes 12 different members in human that mediate the transport of sugars …

[图书][B] Principles of animal nutrition

G Wu - 2017 - taylorfrancis.com
Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

Regulation of coenzyme A levels by degradation: the 'Ins and Outs'

P Naquet, EW Kerr, SD Vickers, R Leonardi - Progress in lipid research, 2020 - Elsevier
Coenzyme A (CoA) is the predominant acyl carrier in mammalian cells and a cofactor that
plays a key role in energy and lipid metabolism. CoA and its thioesters (acyl-CoAs) regulate …

Biofortification of crops with nutrients: factors affecting utilization and storage

J Díaz-Gómez, RM Twyman, C Zhu, G Farré… - Current opinion in …, 2017 - Elsevier
Highlights•Biofortification involves the synthesis or accumulation of nutrients at
source.•Nutrient bioavailability is an intrinsic property that depends on the food …

Cerebral vitamin B5 (D-pantothenic acid) deficiency as a potential cause of metabolic perturbation and neurodegeneration in Huntington's disease

S Patassini, P Begley, J Xu, SJ Church, N Kureishy… - Metabolites, 2019 - mdpi.com
Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG
repeat in exon 1 of the HTT gene. HD usually manifests in mid-life with loss of GABAergic …

Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely affects the immune …

SC Gominak - Medical hypotheses, 2016 - Elsevier
Study objectives Vitamin D blood levels of 60–80 ng/ml promote normal sleep. The present
study was undertaken to explore why this beneficial effect waned after 2 years as arthritic …

Tuning the brightness and photostability of organic dots for multivalent targeted cancer imaging and surgery

H Cong, K Wang, Z Zhou, J Yang, Y Piao, B Yu… - ACS …, 2020 - ACS Publications
Specific labeling of biomarkers with bright and high photostable fluorophores is vital in
fluorescent imaging applications. Here, we report a general strategy to develop single …

Roles of drug transporters in blood-retinal barrier

L Liu, X Liu - Drug Transporters in Drug Disposition, Effects and …, 2019 - Springer
Blood-retinal barrier (BRB) includes inner BRB (iBRB) and outer BRB (oBRB), which are
formed by retinal capillary endothelial (RCEC) cells and by retinal pigment epithelial (RPE) …

Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies

P Begines, A Bonardi, A Nocentini, P Gratteri… - Bioorganic & Medicinal …, 2023 - Elsevier
Sulfonamides constitute an important class of classical carbonic anhydrase (CA, EC 4.2. 1.1)
inhibitors. Herein we have accomplished the conjugation of biotin with an ample number of …