New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects

M Huang, Y Lin, C Wang, L Deng, M Chen… - Drug Resistance …, 2022 - Elsevier
Angiogenesis is a hallmark of cancer and is required for tumor growth and progression.
Antiangiogenic therapy has been revolutionarily developing and was approved for the …

Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma

X Guo, R Sui, H Piao - Journal of Nanobiotechnology, 2022 - Springer
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …

[HTML][HTML] Therapy resistance in neuroblastoma: Mechanisms and reversal strategies

X Zhou, X Wang, N Li, Y Guo, X Yang… - Frontiers in …, 2023 - frontiersin.org
Neuroblastoma is one of the most common pediatric solid tumors that threaten the health of
children, accounting for about 15% of childhood cancer-related mortality in the United …

Role of extracellular vesicles in cancer-specific interactions between tumour cells and the vasculature

L Adnani, C Spinelli, N Tawil, J Rak - Seminars in Cancer Biology, 2022 - Elsevier
Cancer progression impacts and exploits the vascular system in several highly
consequential ways. Among different types of vascular cells, blood cells and mediators that …

Extracellular vesicles in neuroblastoma: role in progression, resistance to therapy and diagnostics

MR Dhamdhere, VS Spiegelman - Frontiers in immunology, 2024 - frontiersin.org
Neuroblastoma (NB) is the most common extracranial solid pediatric cancer, and is one of
the leading causes of cancer-related deaths in children. Despite the current multi-modal …

Label-free nonlinear optical signatures of extracellular vesicles in liquid and tissue biopsies of human breast cancer

JE Sorrells, J Park, E Aksamitiene, M Marjanovic… - Scientific reports, 2024 - nature.com
Extracellular vesicles (EVs) have been implicated in metastasis and proposed as cancer
biomarkers. However, heterogeneity and small size makes assessments of EVs challenging …

Tanshinone IIA promotes vascular normalization and boosts Sorafenib's anti-hepatoma activity via modulating the PI3K-AKT pathway

C Qin, S Liu, S Zhou, X Xia, J Hu, Y Yu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Angiogenesis is an essential feature of liver cancer. Tumor hypoxia results from
abnormal vessel architecture. Numerous studies have sufficiently demonstrated that …

[HTML][HTML] Extracellular vesicles: The future of therapeutics and drug delivery systems

MJ Uddin, P Mohite, S Munde, N Ade, TA Oladosu… - Intelligent …, 2024 - Elsevier
Extracellular vesicles (EVs) are nanometric size, a cell-derived drug delivery carrier
composed of membrane-bound structures, release into the cellular medium and found in …

The Composition of Small Extracellular Vesicles (sEVs) in the Blood Plasma of Colorectal Cancer Patients Reflects the Presence of Metabolic Syndrome and …

NV Yunusova, DA Svarovsky, AI Konovalov… - Journal of Personalized …, 2023 - mdpi.com
The majority of colorectal cancer patients (CRCPs) develop tumors on the background of
“metabolically healthy obesity” or metabolic syndrome. The aim of the work was to study the …

[HTML][HTML] Extracellular Vesicles and Resistance to Anticancer Drugs: A Tumor Skeleton Key for Unhinging Chemotherapies

S Pompili, A Vetuschi, R Sferra, A Cappariello - Frontiers in Oncology, 2022 - frontiersin.org
Although surgical procedures and clinical care allow reaching high success in fighting most
tumors, cancer is still a formidable foe. Recurrence and metastatization dampen the patients' …