Precision diagnosis and treatment of liver cancer in China

J Fu, H Wang - Cancer letters, 2018 - Elsevier
Liver cancer ranks the sixth in cancer incidence and the second in tumor related mortality
worldwide, with over half of the new cases and deaths occur in China. Because of difficulties …

Inflammatory mechanisms of HCC development

MG Refolo, C Messa, V Guerra, BI Carr… - Cancers, 2020 - mdpi.com
HCC (hepatocellular carcinoma) is the second leading cause of cancer deaths worldwide,
with several etiologic causes, mostly inflammation-associated. Different inflammatory …

Heterogeneity of liver cancer and personalized therapy

L Li, H Wang - Cancer letters, 2016 - Elsevier
Liver cancer is an extraordinarily heterogeneous malignant disease among the tumors that
have so far been identified. Hepatocellular carcinoma (HCC) arises most frequently in the …

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

MA Karsdal, T Manon-Jensen… - American Journal …, 2015 - journals.physiology.org
Emerging evidence suggests that altered components and posttranslational modifications of
proteins in the extracellular matrix (ECM) may both initiate and drive disease progression …

Advances and perspectives in fluorescent probes for imaging hepatopathy-related biomarkers

W Quan, W Song, Q Zhang, H Huang, W Lin - Coordination Chemistry …, 2023 - Elsevier
As the metabolic and detoxification center of the body, the liver is closely involved in many
critical physiological processes, such as metabolism, immunity, digestion, storage of liver …

Liver cirrhosis contributes to the disorder of gut microbiota in patients with hepatocellular carcinoma

R Zheng, G Wang, Z Pang, N Ran, Y Gu… - Cancer …, 2020 - Wiley Online Library
Background Gut microbiota (GM) of patients with liver cancer is disordered, and syet no
study reported the GM distribution of liver cirrhosis‐induced HCC (LC‐HCC) and nonliver …

Molecular subtyping of hepatocellular carcinoma: A step toward precision medicine

Y Wu, Z Liu, X Xu - Cancer Communications, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal digestive tumors.
Treatment for this disease has been constraint by heterogeneity of this group of tumors …

PPARγ signaling in hepatocarcinogenesis: mechanistic insights for cellular reprogramming and therapeutic implications

SM Ishtiaq, MI Arshad, JA Khan - Pharmacology & Therapeutics, 2022 - Elsevier
Liver cancer or hepatocellular carcinoma (HCC) is leading cause of cancer-related
mortalities globally. The therapeutic approaches for chronic liver diseases-associated liver …

Chronic viral hepatitis and its association with liver cancer

T Tu, S Bühler, R Bartenschlager - Biological chemistry, 2017 - degruyter.com
Chronic infection with hepatitis viruses represents the major causative factor for end-stage
liver diseases, including liver cirrhosis and primary liver cancer (hepatocellular carcinoma …

Alteration in gut microbiota associated with hepatitis B and non-hepatitis virus related hepatocellular carcinoma

Q Liu, F Li, Y Zhuang, J Xu, J Wang, X Mao, Y Zhang… - Gut pathogens, 2019 - Springer
Background The onset of hepatocellular carcinoma (HCC) ranked fifth malignancies all over
the world. Increasing evidences showed that the distribution of HCC was related to the …