Monkeypox: disease epidemiology, host immunity and clinical interventions
Monkeypox virus (MPXV), which causes disease in humans, has for many years been
restricted to the African continent, with only a handful of sporadic cases in other parts of the …
restricted to the African continent, with only a handful of sporadic cases in other parts of the …
Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …
saved several lives, reduced treatment costs and raised the quality of animal and human …
Balancing natural killer cell activation through paired receptors
L Martinet, MJ Smyth - Nature Reviews Immunology, 2015 - nature.com
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections
and malignancies. NK cells express a variety of inhibitory and activating receptors that …
and malignancies. NK cells express a variety of inhibitory and activating receptors that …
Liver-resident NK cells confer adaptive immunity in skin-contact inflammation
H Peng, X Jiang, Y Chen, DK Sojka… - The Journal of …, 2013 - Am Soc Clin Investig
Liver natural killer (NK) cells were recently reported to possess memory-like properties in
contact hypersensitivity (CHS) models. However, the phenotype and origin of these …
contact hypersensitivity (CHS) models. However, the phenotype and origin of these …
Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses
Hepatic natural killer (NK) cells mediate antigen-specific contact hypersensitivity (CHS) in
mice deficient in T cells and B cells. We report here that hepatic NK cells, but not splenic or …
mice deficient in T cells and B cells. We report here that hepatic NK cells, but not splenic or …
Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors
DC Ifrim, J Quintin, LAB Joosten, C Jacobs… - Clinical and Vaccine …, 2014 - Am Soc Microbiol
Upon priming with Candida albicans or with the fungal cell wall component β-glucan,
monocytes respond with an increased cytokine production upon restimulation, a …
monocytes respond with an increased cytokine production upon restimulation, a …
[HTML][HTML] An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele
Natural killer (NK) cells are known to play a role in mediating innate immunity, in enhancing
adaptive immune responses, and have been implicated in mediating anti-tumor responses …
adaptive immune responses, and have been implicated in mediating anti-tumor responses …
Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis
S Kurgan, A Kantarci - Periodontology 2000, 2018 - Wiley Online Library
Two common diseases–gingivitis and periodontitis–affect the periodontium. Symptoms of
disease entities are used for distinguishing various forms of gingivitis and periodontitis …
disease entities are used for distinguishing various forms of gingivitis and periodontitis …
The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity
Considerable evidence has been gathered over the last 10 years showing that the tumor
microenvironment (TME) is not simply a passive recipient of immune cells, but an active …
microenvironment (TME) is not simply a passive recipient of immune cells, but an active …
γδ T cells exhibit multifunctional and protective memory in intestinal tissues
BS Sheridan, PA Romagnoli, QM Pham, HH Fu… - Immunity, 2013 - cell.com
The study of T cell memory and the target of vaccine design have focused on memory
subsumed by T cells bearing the αβ T cell receptor. Alternatively, γδ T cells are thought to …
subsumed by T cells bearing the αβ T cell receptor. Alternatively, γδ T cells are thought to …