Prospects of surface-enhanced Raman spectroscopy for biomarker monitoring toward precision medicine
Future precision medicine will be undoubtedly sustained by the detection of validated
biomarkers that enable a precise classification of patients based on their predicted disease …
biomarkers that enable a precise classification of patients based on their predicted disease …
A tutorial review: Metabolomics and partial least squares-discriminant analysis–a marriage of convenience or a shotgun wedding
The predominance of partial least squares-discriminant analysis (PLS-DA) used to analyze
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …
Using Raman spectroscopy to characterize biological materials
Raman spectroscopy can be used to measure the chemical composition of a sample, which
can in turn be used to extract biological information. Many materials have characteristic …
can in turn be used to extract biological information. Many materials have characteristic …
SERS-based antibiotic susceptibility testing: Towards point-of-care clinical diagnosis
Emerging antibiotic resistant bacteria constitute one of the biggest threats to public health.
Surface-enhanced Raman scattering (SERS) is highly promising for detecting such bacteria …
Surface-enhanced Raman scattering (SERS) is highly promising for detecting such bacteria …
[HTML][HTML] An evaluation of fixation methods: Spatial and compositional cellular changes observed by Raman imaging
AJ Hobro, NI Smith - Vibrational Spectroscopy, 2017 - Elsevier
Although live cell imaging is desirable, it is not always feasible and in many situations cells
are fixed in order to provide a 'snapshot'of the nature and distribution of molecules within a …
are fixed in order to provide a 'snapshot'of the nature and distribution of molecules within a …
Sensing using plasmonic nanostructures and nanoparticles
Nanoparticles are widely used in various fields of science and technology as well as in
everyday life. In particular, gold and silver nanoparticles display unique optical properties …
everyday life. In particular, gold and silver nanoparticles display unique optical properties …
Raman spectroscopy: an emerging tool in neurodegenerative disease research and diagnosis
G Devitt, K Howard, A Mudher… - ACS chemical …, 2018 - ACS Publications
The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …
understood. The lack of effective biomarkers and disease preventative medicine demands …
[HTML][HTML] Point-and-shoot: rapid quantitative detection methods for on-site food fraud analysis–moving out of the laboratory and into the food supply chain
Major food adulteration and contamination events occur with alarming regularity and are
known to be episodic, with the question being not if but when another large-scale food …
known to be episodic, with the question being not if but when another large-scale food …
Clinical applications of infrared and Raman spectroscopy: state of play and future challenges
Vibrational spectroscopies, based on infrared absorption and/or Raman scattering provide a
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …
detailed fingerprint of a material, based on the chemical content. Diagnostic and prognostic …
Noninvasive detection of macrophage activation with single-cell resolution through machine learning
N Pavillon, AJ Hobro, S Akira… - Proceedings of the …, 2018 - National Acad Sciences
We present a method enabling the noninvasive study of minute cellular changes in
response to stimuli, based on the acquisition of multiple parameters through label-free …
response to stimuli, based on the acquisition of multiple parameters through label-free …