Pharmacological treatment of Parkinson's disease

I Zahoor, A Shafi, E Haq - Exon Publications, 2018 - exonpublications.com
Parkinson's disease (PD) is one of the common chronic degenerative conditions of the
nervous system. There is currently no cure for PD, but a number of drugs offer benefits in …

[HTML][HTML] Impulse control disorders in Parkinson's disease. A brief and comprehensive review

EM Gatto, V Aldinio - Frontiers in neurology, 2019 - frontiersin.org
Impulse control and related disorders (ICDs-RD) encompasses a heterogeneous group of
disorders that involve pleasurable behaviors performed repetitively, excessively, and …

[HTML][HTML] Treatment of Parkinson's disease through personalized medicine and induced pluripotent stem cells

T Stoddard-Bennett, R Reijo Pera - Cells, 2019 - mdpi.com
Parkinson's Disease (PD) is an intractable disease resulting in localized neurodegeneration
of dopaminergic neurons of the substantia nigra pars compacta. Many current therapies of …

Sex and gender differences in Parkinson's disease

R Patel, K Kompoliti - Neurologic Clinics, 2023 - neurologic.theclinics.com
Parkinson's disease (PD) is the second most common neurodegenerative disease affecting
older adults, and it is approximately twice as common in males compared with females. 1 …

[HTML][HTML] Long-term safety and efficacy of apomorphine infusion in Parkinson's disease patients with persistent motor fluctuations: results of the open-label phase of the …

R Katzenschlager, W Poewe, O Rascol… - Parkinsonism & related …, 2021 - Elsevier
Introduction The randomized, double-blind phase (DBP) of the TOLEDO study confirmed the
efficacy of apomorphine infusion (APO) in reducing OFF time in PD patients with persistent …

[HTML][HTML] Autophagy-lysosomal pathway as potential therapeutic target in Parkinson's disease

SR Bonam, C Tranchant, S Muller - Cells, 2021 - mdpi.com
Cellular quality control systems have gained much attention in recent decades. Among
these, autophagy is a natural self-preservation mechanism that continuously eliminates toxic …

[HTML][HTML] Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings

L Ricciardi, M Apps, S Little - npj Parkinson's Disease, 2023 - nature.com
Neuropsychiatric mood and motivation symptoms (depression, anxiety, apathy, impulse
control disorders) in Parkinson's disease (PD) are highly disabling, difficult to treat and …

Impulse control disorders in hyperprolactinemic patients on dopamine agonist therapy

A Hamidianjahromi, NA Tritos - Reviews in Endocrine and Metabolic …, 2022 - Springer
Dopamine agonists (DAs) represent a mainstay of therapy for hyperprolactinemia and
prolactinomas. The widespread use of DAs, including bromocriptine, cabergoline and (in …

Management of Impulse Control and Related Disorders in Parkinson's Disease: An Expert Consensus

I Debove, S Paschen, D Amstutz, F Cardoso… - Movement …, 2024 - Wiley Online Library
Background Impulse‐control and related behavioral disorders (ICBDs) significantly impact
the lives of Parkinson's disease (PD) patients and caregivers, with lasting consequences if …

Treatment for cognitive and neuropsychiatric non-motor symptoms in Parkinson's disease: current evidence and future perspectives

E Mantovani, C Zucchella, AA Argyriou… - Expert Review of …, 2023 - Taylor & Francis
Introduction Non-motor symptoms (NMS) affect patients with Parkinson's disease (PD) from
the prodromal to the advanced stages. NMS phenotypes greatly vary and have a huge …