The role of inflammation and genetics in periodontal disease

BG Loos, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Gut microbiota is a potential biomarker in inflammatory bowel disease

X Guo, C Huang, J Xu, H Xu, L Liu, H Zhao… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's
disease (CD), is characterized by relapse and remission alternately. It remains a great …

Nutrition, IBD and gut microbiota: a review

MC Mentella, F Scaldaferri, M Pizzoferrato… - Nutrients, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract, characterized by an inflammatory process that requires lifelong …

The human gut microbiome in health and disease

J Jovel, LA Dieleman, D Kao, AL Mason, E Wine - Metagenomics, 2018 - Elsevier
The harmonic coexistence of microorganisms with the human body is the result of a long
coevolutionary process that has minimized competition for nutrients and immunological …

Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease

AR Weingarden, BP Vaughn - Gut microbes, 2017 - Taylor & Francis
Inflammatory bowel disease (IBD) is a complex set of diseases that lead to chronic
inflammation in the gastrointestinal tract. Although the etiology of IBD is not fully understood …

Clonal hematopoiesis, somatic mosaicism, and age-associated disease

MA Evans, K Walsh - Physiological Reviews, 2023 - journals.physiology.org
Somatic mosaicism, the occurrence of multiple genetically distinct cell clones within the
same tissue, is an evitable consequence of human aging. The hematopoietic system is no …

Dysbiosis of gut microbiota in promoting the development of colorectal cancer

S Zou, L Fang, MH Lee - Gastroenterology report, 2018 - academic.oup.com
Gastrointestinal microbiome, containing at least 100 trillion bacteria, resides in the mucosal
surface of human intestine. Recent studies show that perturbations in the microbiota may …

Immunomodulating activity and therapeutic effects of short chain fatty acids and tryptophan post-biotics in inflammatory bowel disease

E Russo, F Giudici, C Fiorindi, F Ficari… - Frontiers in …, 2019 - frontiersin.org
Crohn's disease (CD) and Ulcerative colitis (UC) are grouped as Inflammatory Bowel
Diseases (IBD). The IBD is associated to a multifaceted interplay between immunologic …

Propionate ameliorates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress

L Tong, Y Wang, Z Wang, W Liu, S Sun, L Li… - Frontiers in …, 2016 - frontiersin.org
Propionate is a short chain fatty acid that is abundant as butyrate in the gut and blood.
However, propionate has not been studied as extensively as butyrate in the treatment of …

Location-specific signatures of Crohn's disease at a multi-omics scale

CG Gonzalez, RH Mills, Q Zhu, C Sauceda, R Knight… - Microbiome, 2022 - Springer
Background Crohn's disease (CD), an inflammatory bowel disease (IBD) subtype, results
from pathologic interactions between host cells and its resident gut microbes. CD manifests …