AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …

Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

The link between gut microbiome and brain is being slowly acknowledged due to the
speculated role of resident gut microbial community in altering the functions of gut-brain axis …

Progress toward the development of efficacious therapies for Alzheimer's disease (AD) is
halted by a lack of understanding early underlying pathological mechanisms. Systems …

Note added by the Publisher: The editors of the journal have been alerted to concerns over
potential bias in opinions and bias in the choice of citation sources used in this article. We …

The continued drug discovery failures in complex neurodegenerative diseases, including
Alzheimer's disease (AD), has raised questions about the classical paradigm “one‐drug …

Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

Neurodegenerative diseases represent nowadays one of the major health problems.
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …

Importance New therapeutic approaches for Alzheimer disease (AD) are needed. Objective
To assess whether idalopirdine, a selective 5-hydroxytryptamine-6 receptor antagonist, is …

Abstract Research has shown that psychedelics, such as lysergic acid diethylamide (LSD),
have profound anti-inflammatory properties mediated by 5-HT 2A receptor signaling …