Turning on the light within: subcortical nuclei of the isodentritic core and their role in Alzheimer's disease pathogenesis
P Theofilas, S Dunlop, H Heinsen… - Journal of Alzheimer's …, 2015 - content.iospress.com
Pharmacological interventions in Alzheimer's disease (AD) are likely to be more efficacious
if administered early in the course of the disease, foregoing the spread of irreversible …
if administered early in the course of the disease, foregoing the spread of irreversible …
Selective serotonin reuptake inhibitors and Alzheimer's disease
Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …
strategies aiming at preventing or delaying the onset of the disease are being prioritized …
[HTML][HTML] Synthesis, computational and experimental pharmacological studies for (thio) ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and …
K Czarnota-Łydka, S Sudoł-Tałaj… - European Journal of …, 2023 - Elsevier
Alzheimer's disease is becoming a growing problem increasing at a tremendous rate.
Serotonin 5-HT 6 receptors appear to be a particularly attractive target from a therapeutic …
Serotonin 5-HT 6 receptors appear to be a particularly attractive target from a therapeutic …
Novel multi-target-directed ligands for Alzheimer's disease: combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological …
As currently postulated, a complex treatment may be key to an effective therapy for
Alzheimer's disease (AD). Recent clinical trials in patients with moderate AD have shown a …
Alzheimer's disease (AD). Recent clinical trials in patients with moderate AD have shown a …
Psychedelics for Alzheimer's disease-related dementia: Unveiling therapeutic possibilities and pathways
Psychedelics have traditionally been used for spiritual and recreational purposes, but recent
developments in psychotherapy have highlighted their potential as therapeutic agents …
developments in psychotherapy have highlighted their potential as therapeutic agents …
Antagonism of the 5-HT6 receptor–Preclinical rationale for the treatment of Alzheimer's disease
IEM de Jong, A Mørk - Neuropharmacology, 2017 - Elsevier
Antagonism of the 5-HT 6 receptor is a promising approach for the symptomatic treatment of
Alzheimer's disease (AD). There is compelling preclinical evidence for the procognitive …
Alzheimer's disease (AD). There is compelling preclinical evidence for the procognitive …
Highlighting immune system and stress in major depressive disorder, Parkinson's, and Alzheimer's diseases, with a connection with serotonin
AS Correia, A Cardoso, N Vale - International Journal of Molecular …, 2021 - mdpi.com
There is recognition that both stress and immune responses are important factors in a variety
of neurological disorders. Moreover, there is an important role of several neurotransmitters …
of neurological disorders. Moreover, there is an important role of several neurotransmitters …
Gut biofactory—Neurocompetent metabolites within the gastrointestinal tract. A scoping review
K Skonieczna-Żydecka, K Jakubczyk… - Nutrients, 2020 - mdpi.com
The gut microbiota have gained much scientific attention recently. Apart from unravelling the
taxonomic data, we should understand how the altered microbiota structure corresponds to …
taxonomic data, we should understand how the altered microbiota structure corresponds to …
Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status
Alzheimer's disease (AD) is the most common cause of dementia in elderly people.
Research focused on identifying compounds that restore cognition and memory in AD …
Research focused on identifying compounds that restore cognition and memory in AD …
Monoaminergic and histaminergic strategies and treatments in brain diseases
The monoaminergic systems are the target of several drugs for the treatment of mood, motor
and cognitive disorders as well as neurological conditions. In most cases, advances have …
and cognitive disorders as well as neurological conditions. In most cases, advances have …