[HTML][HTML] The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

[HTML][HTML] Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

[HTML][HTML] Recent advances in understanding the structure and function of the human microbiome

WK Mousa, F Chehadeh, S Husband - Frontiers in Microbiology, 2022 - frontiersin.org
Trillions of microbes live within our bodies in a deep symbiotic relationship. Microbial
populations vary across body sites, driven by differences in the environment, immunological …

[HTML][HTML] Commensal bacteria of the lung microbiota synergistically inhibit inflammation in a three-dimensional epithelial cell model

E Goeteyn, L Grassi, S Van den Bossche… - Frontiers in …, 2023 - frontiersin.org
Patients with chronic lung disease suffer from persistent inflammation and are typically
colonized by pro-inflammatory pathogenic bacteria. Besides these pathogens, a wide variety …

[HTML][HTML] The use of exhaled air analysis in discriminating interstitial lung diseases: a pilot study

L Plantier, A Smolinska, R Fijten, M Flamant… - Respiratory …, 2022 - Springer
Abstract Background Fibrotic Interstitial lung diseases (ILD) are a heterogeneous group of
chronic lung diseases characterized by diverse degrees of lung inflammation and …

The role of the host-microbiome and metabolomics in sarcoidosis

J Kim, S Lee, Y Moodley, L Yagnik… - … of Physiology-Cell …, 2023 - journals.physiology.org
Sarcoidosis is a complex inflammatory fibrotic disease that affects multiple organ systems. It
is characterized by the infiltration of lymphocytes and mononuclear phagocytes, which form …

[HTML][HTML] The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis

KS Knudsen, S Lehmann, R Nielsen, S Tangedal… - Microbiome, 2022 - Springer
Background The role of the pulmonary microbiome in sarcoidosis is unknown. The
objectives of this study were the following:(1) examine whether the pulmonary fungal and …

[HTML][HTML] Biomarkers and molecular endotypes of sarcoidosis: lessons from omics and non-omics studies

HL Ji, NMS Xi, C Mohan, X Yan, KG Jain… - Frontiers in …, 2024 - frontiersin.org
Sarcoidosis is a chronic granulomatous disorder characterized by unknown etiology,
undetermined mechanisms, and non-specific therapies except TNF blockade. To improve …

[HTML][HTML] Culture-independent exploration of the hypersaline ecosystem indicates the environment-specific microbiome evolution

P Mehta, M Yadav, V Ahmed, K Goyal… - Frontiers in …, 2021 - frontiersin.org
Sambhar Salt Lake, situated in the state of Rajasthan, India is a unique temperate
hypersaline ecosystem. Exploration of the salt lake microbiome will enable us to understand …

The mechanism of Qingwen Gupi decoction on pulmonary fibrosis based on metabolomics and intestinal flora

C Gao, H Chang, Z Wang, M Jia, Q Li… - Journal of Applied …, 2023 - academic.oup.com
Aims To evaluate the effects of the Qingwen Gupi decoction (QGT) in a rat model of
bleomycin-induced pulmonary fibrosis (PF), and explore the underlying mechanisms by …