Antioxidant vitamins and prevention of cardiovascular disease: epidemiological and clinical trial data
R Marchioli, C Schweiger, G Levantesi, L Tavazzi… - Lipids, 2001 - Wiley Online Library
Naturally occurring antioxidants such as vitamin E, β‐carotene, and vitamin C can inhibit the
oxidative modification of low density lipoproteins. This action could positively influence the …
oxidative modification of low density lipoproteins. This action could positively influence the …
Increased levels of soluble P-selectin in hypercholesterolemic patients
Background—Hypercholesterolemia is considered a major risk factor for the development of
atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be …
atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be …
Endothelial dysfunction and oxidative stress in arterial hypertension
A large body of evidence indicates that endothelial dysfunction is a characteristic of patients
with essential hypertension. By definition, endothelial dysfunction is a functional and …
with essential hypertension. By definition, endothelial dysfunction is a functional and …
Reduced sensitivity of platelets from type 2 diabetic patients to acetylsalicylic acid (aspirin)—its relation to metabolic control
C Watala, J Golanski, J Pluta, M Boncler, M Rozalski… - Thrombosis …, 2004 - Elsevier
Aspirin (acetylsalicylic acid, ASA), which is recommended for primary and secondary
prevention in diabetes mellitus (DM), has been shown to have a lower antiplatelet activity in …
prevention in diabetes mellitus (DM), has been shown to have a lower antiplatelet activity in …
Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure
MA Forgione, A Cap, R Liao, NI Moldovan… - Circulation, 2002 - Am Heart Assoc
Background—Oxidant stress has been implicated in the pathogenesis of atherothrombosis
and other vascular disorders accompanied by endothelial dysfunction. Glutathione …
and other vascular disorders accompanied by endothelial dysfunction. Glutathione …
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease
P Minuz, P Patrignani, S Gaino, M Degan… - Circulation, 2002 - Am Heart Assoc
Background—Hypertensive patients with renovascular disease (RVD) may be exposed to
increased oxidative stress, possibly related to activation of the renin-angiotensin system …
increased oxidative stress, possibly related to activation of the renin-angiotensin system …
Cellular glutathione peroxidase deficiency and endothelial dysfunction
MA Forgione, N Weiss, S Heydrick… - … of physiology-heart …, 2002 - journals.physiology.org
Cellular glutathione peroxidase (GPx-1) is the most abundant intracellular isoform of the
GPx antioxidant enzyme family. In this study, we hypothesized that GPx-1 deficiency directly …
GPx antioxidant enzyme family. In this study, we hypothesized that GPx-1 deficiency directly …
F2-isoprostanes as an indicator and risk factor for coronary heart disease
SS Davies, LJ Roberts II - Free Radical Biology and Medicine, 2011 - Elsevier
Coronary heart disease (CHD) is the leading single cause of death in the United States and
most Western countries, killing more than 400,000 Americans per year. Although CHD often …
most Western countries, killing more than 400,000 Americans per year. Although CHD often …
Olive phenol hydroxytyrosol prevents passive smoking–induced oxidative stress
F Visioli, C Galli, E Plasmati, S Viappiani… - Circulation, 2000 - Am Heart Assoc
Background—Oxidative stress is involved in the onset of several degenerative disorders,
and epidemiological studies indicate that a high intake of dietary antioxidants, as in the case …
and epidemiological studies indicate that a high intake of dietary antioxidants, as in the case …
Comparison of the effect of α-lipoic acid and α-tocopherol supplementation on measures of oxidative stress
In vitro studies have shown that α-lipoic acid (LA) is an antioxidant. There is a paucity of
studies on LA supplementation in humans. Therefore, the aim of this study was to assess the …
studies on LA supplementation in humans. Therefore, the aim of this study was to assess the …