Diabetes mellitus has become a serious and chronic metabolic disorder that results from a
complex interaction of genetic and environmental factors, principally characterized by …

There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

Marine algae are rich in bioactive nutraceuticals (eg, carbohydrates, proteins, minerals, fatty
acids, antioxidants, and pigments). Biotic (eg, plants, microorganisms) and abiotic factors …

AIM To investigate whether immune mediated diseases (IMD) are more frequent in patients
with inflammatory bowel disease (IBD). METHODS In this population based registry study, a …

Diabetic cardiomyopathy (DCM) is often associated with suppressed cardiac autophagy,
mitochondrial structural and functional impairment. Sirtuin-3 (Sirt3) has been reported to …

Immune-targeted therapies have efficacy for treatment of autoinflammatory diseases. For
example, treatment with the T cell–specific anti-CD3 antibody teplizumab delayed disease …

For decades, research in autoimmunity has focused primarily on immune contributions to
disease. Yet recent studies report elevated levels of reactive oxygen species and abnormal …

Vitiligo is a disease of the skin characterized by the appearance of white spots. Significant
progress has been made in understanding vitiligo pathogenesis over the past 30 years, but …

Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity.
Here we show, by analyzing> 2× 108 TCRB sequences of circulating naive, central memory …

Pancreatic ACE2 receptor expression, together with increased prevalence of insulin-
requiring hyperglycemia in patients with coronavirus disease 2019 (COVID-19), suggested …