[HTML][HTML] Neurokinin 1/3 receptor antagonists for menopausal women: A current systematic review and insights into the investigational non-hormonal therapy

F Hassan, A Saleem, SS Samuel, Z Sarfraz, A Sarfraz… - Medicine, 2023 - journals.lww.com
Background: Over 75% of menopausal women experience vasomotor symptoms (VMS),
such as night sweats and hot flashes. Despite the prevalence of these symptoms, there is …

[HTML][HTML] Changes of Signaling Pathways in Hypothalamic Neurons with Aging

PM Masliukov - Current Issues in Molecular Biology, 2023 - mdpi.com
The hypothalamus is an important regulator of autonomic and endocrine functions also
involved in aging regulation. The aging process in the hypothalamus is accompanied by …

Mechanism of arcuate kisspeptin neuron synchronization in acute brain slices from female mice

PG Morris, AE Herbison - Endocrinology, 2023 - academic.oup.com
The mechanism by which arcuate kisspeptin (ARNKISS) neurons co-expressing glutamate,
neurokinin B, and dynorphin intermittently synchronize their activity to drive pulsatile …

The preoptic Kisspeptin/nNOS/GnRH (KiNG) neuronal network regulates rhythmic LH release through a dual activation-inhibition mechanism

V Delli, CA Seux, J Dehame, S Nair, T Lhomme… - bioRxiv, 2024 - biorxiv.org
Gonadotropin-releasing hormone (GnRH) neurons are the final common target of a complex
network of cells cooperating for the central control of reproduction. The balance between …

Endocrine Disruptors and Metabolic Changes: Impact on Puberty Control

M Peralta, F Lizcano - Endocrine Practice, 2024 - Elsevier
Objective This study aims to explore the significant impact of environmental chemicals on
disease development, focusing on their role in developing metabolic and endocrine …

Mechanism of arcuate kisspeptin neuron synchronization in acute brain slices from female mice

A Herbison, P Morris - 2023 - repository.cam.ac.uk
The mechanism by which arcuate kisspeptin (ARNKISS) neurons co-expressing glutamate,
neurokinin B, and dynorphin intermittently synchronize their activity to drive pulsatile …

Novel regulatory mechanisms of Kiss1 neurons during reproductive axis development and in conditions of metabolic stress: Analysis of the roles of microRNAs and …

M Ruiz Cruz - 2023 - helvia.uco.es
Reproduction is indispensable for the perpetuation of the species. Therefore, it is
safeguarded by a sophisticated network of regulatory mechanisms that ultimately controls …