[HTML][HTML] Opioid use disorder: current trends and potential treatments

YK Lee, MS Gold, K Blum, PK Thanos… - Frontiers in Public …, 2024 - frontiersin.org
Opioid use disorder (OUD) is a major public health threat, contributing to morbidity and
mortality from addiction, overdose, and related medical conditions. Despite our increasing …

[HTML][HTML] Implementing core genes and an omnigenic model for behaviour traits prediction in genomics

T Rancelis, I Domarkiene, L Ambrozaityte, A Utkus - Genes, 2023 - mdpi.com
A high number of genome variants are associated with complex traits, mainly due to genome-
wide association studies (GWAS). Using polygenic risk scores (PRSs) is a widely accepted …

[HTML][HTML] High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

J Tyler, M Podaras, B Richardson, N Roeder… - Frontiers in Public …, 2023 - frontiersin.org
Background Previous research has outlined the health benefits of exercise including its
therapeutic potential for substance use disorders (SUD). These data have already been …

Potential Link Between Exercise and N-Methyl-D-Aspartate Glutamate Receptors in Alcohol Use Disorder: Implications for Therapeutic Strategies

S Sedhom, N Hammond, KZ Thanos… - Psychology Research …, 2024 - Taylor & Francis
Alcohol use disorder (AUD) is a significant risk factor, accounting for approximately 13% of
all deaths in the US. AUD not only destroys families but also causes economic losses due to …

[HTML][HTML] Invited Expert Opinion-Bioinformatic and Limitation Directives to Help Adopt Genetic Addiction Risk Screening and Identify Preaddictive Reward …

K Blum, MS Gold, JL Cadet… - Medical research …, 2023 - ncbi.nlm.nih.gov
Addiction, albeit some disbelievers like Mark Lewis [1], is a chronic, relapsing brain disease,
resulting in unwanted loss of control over both substance and non-substance behavioral …

Personalized repetitive transcranial magnetic stimulation guided by the spectral electroencephalogram may enhance and democratize therapy for autism spectrum …

MT Makale, K Blum, A Bowirrat, K Sunder… - Medical …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a genetically heterogeneous group of
neurodevelopmental disorders that affect 1 in 36 children (CDC data) and have …

[HTML][HTML] Addressing cortex dysregulation in youth through brain health check coaching and prophylactic brain development

K Blum, ER Braverman, MS Gold… - INNOSC theranostics …, 2024 - ncbi.nlm.nih.gov
Abstract The Carter Center has estimated that the addiction crisis in the United States (US), if
continues to worsen at the same rate, may cost the country approximately 16 trillion dollars …

Neurogenetics and epigenetics of loneliness

A Bowirrat, I Elman, CA Dennen… - Psychology research …, 2023 - Taylor & Francis
Loneliness, an established risk factor for both, mental and physical morbidity, is a mounting
public health concern. However, the neurobiological mechanisms underlying loneliness …