Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …

Molecular hybridization is one of the recent stratagems in medicinal chemistry to synthesize
a novel hybrid molecule having better affinity and efficacy by combining two or more …

The current study investigated the cytotoxic effect of ten sulfonamide-derived isatins,
following molecular hybridization, based on the association principles, on hepatocellular …

SARS-CoV-2 and its variants, especially the Omicron variant, remain a great threat to human
health. The need to discover potent compounds that may control the SARS-CoV-2 virus …

In the present work, new benzimidazole linked 1, 2, 3-triazole hybrids have been
synthesized and screened for antiproliferative and EGFR kinase inhibitory activities. The …

Abstract Design, synthesis, spectral characterization and antimicrobial evaluation of a series
of twelve chalcone-containing amide linked 1, 4-disubstituted 1, 2, 3-triazole hybrids and …

This study reports an efficient and convenient click chemistry synthesis of a novel series of
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …

A series of coumarin appended triazole hybrids of biotic interest was synthesized through
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …

In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …

This study reports an efficient and convenient click synthesis of novel series of chromene
scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments. Structures of all newly …