This was a 1-year, prospective, multicentric cohort study conducted in Slovakia. Adult
outpatients 30 with diagnosis of schizophrenia according to ICD-10 and PNS evaluated …

Background Administration of valproic acid (VPA) is complicated with approximately 0.9% of
patients developing hyperammonemia, but the pathogenesis of this adverse effect remains …

Introduction The aim of the study was to evaluate interaction effect of various augmentation
strategies with clozapine in patients with Treatment-resistant schizophrenia. Methods Data …

Background: Up to 34% of patients with schizophrenia are resistant to several treatment
trials. Lack of continuous and adequate treatment is associated with relapse …

Clozapine is the only approved antipsychotic for treatment-resistant schizophrenia (TRS).
Although a large body of evidence supports its efficacy and favorable risk-benefit ratio in …

Background This prospective cohort study aimed at evaluating patterns of polypharmacy
and aggressive and violent behavior during a 1-year follow-up in patients with severe …

Background There is little evidence to support the use of antipsychotic polypharmacy, and
there are concerns about safety and side effects. Nonetheless, it is commonly used in the …

In this study, the rates of antipsychotic polypharmacy, factors affecting combined drug use,
the relationship between antipsychotic polypharmacy as it relates to duration of …

Ichihashi et al reported that 43% of patients had antipsychotic polypharmacy. Number of
antipsychotics used in patients with schizophrenia in Japan was the greatest among Asian …

Zusammenfassung Indikationen, Wirkungsweise, Nebenwirkungen und Risiken,
Kontraindikationen und Interaktionen werden für die Antipsychotika im allgemeinen Teil und …