[HTML][HTML] c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment

F Gao, X Li, K Xu, R Wang, X Guan - Cell Communication and Signaling, 2023 - Springer
The MYC oncogenic family is dysregulated in diverse tumors which is generally linked to the
poor prognosis of tumors. The members in MYC family are transcription factors which are …

Immune-inflammatory modulation by natural products derived from edible and medicinal herbs used in Chinese classical prescriptions

Q Kang, L He, Y Zhang, Z Zhong, W Tan - Phytomedicine, 2024 - Elsevier
Background Edible and medicinal herbs 1 (EMHs) refer to a class of substances with dual
attribution of food and medicine. These substances are traditionally used as food and also …

[HTML][HTML] Extracellular matrix derived from Wharton's Jelly-derived mesenchymal stem cells promotes angiogenesis via integrin αVβ3/c-Myc/P300/VEGF

B Ma, T Wang, J Li, Q Wang - Stem cell research & therapy, 2022 - Springer
Background Angiogenesis is required in many physiological conditions, including bone
regeneration, wound healing, and tissue regeneration. Mesenchymal stem cells-derived …

[HTML][HTML] Controlled delivery of pan-PAD-inhibitor Cl-amidine using poly (3-hydroxybutyrate) microspheres

D Ahmed, H Puthussery, P Basnett… - International Journal of …, 2021 - mdpi.com
This study deals with the process of optimization and synthesis of Poly (3-hydroxybutyrate)
microspheres with encapsulated Cl-amidine. Cl-amidine is an inhibitor of peptidylarginine …

[HTML][HTML] Antiproliferative Modulation and Pro-Apoptotic Effect of BR2 Tumor-Penetrating Peptide Formulation 2-Aminoethyl Dihydrogen Phosphate in Triple-Negative …

LGS Cabral, CS Oliveira, KA Freire, MG Alves… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is an aggressive, hard-to-treat form
of breast cancer, accounting for about 15 percent of breast cancers. The aim of our study …

DNA interactive property of poly‐L‐lysine induces apoptosis in MCF‐7 cells through DNA interaction

A Mukherjee, S Debnath, A Bhowmik… - Journal of Biochemical …, 2023 - Wiley Online Library
Abstract Poly‐L‐lysine (PLL) is known to be an encapsulating agent in drug formulation and
delivery. PLL also has apoptotic and antiproliferative activities that enable blocking of the …

[HTML][HTML] ARHGEF2/EDN1 pathway participates in ER stress-related drug resistance of hepatocellular carcinoma by promoting angiogenesis and malignant …

Y Zhu, W Liu, Z Wang, Y Wang, C Tan, Z Pan… - Cell Death & …, 2022 - nature.com
Endoplasmic reticulum (ER) stress is widely involved in the drug resistance of hepatocellular
carcinoma (HCC), but the mechanism of ER stress-induced drug resistance involves …

Unraveling the Complex Interplay between lncRNAs and Myc in Breast Cancer

SP Mirmazhari, MJ Abdi, AH Mosadeghrad, RA Bonab… - 2023 - preprints.org
The Myc gene, widely studied in numerous cancer types, serves as a pivotal regulator of
crucial cellular processes implicated in tumorigenesis, such as cell growth, proliferation …

[PDF][PDF] 基于靶向调控肿瘤血管的新型纳米递药系统研究进展

高春晓, 方峥瑜, 汤湛, 俞文英 - 中国药学杂志, 2022 - journal11.magtechjournal.com
高度紊乱的血管系统是恶性实体肿瘤的共性特征, 肿瘤血管与肿瘤的发生及发展有着紧密的联系
, 因而肿瘤血管靶向治疗已成为肿瘤治疗领域的重要组成部分, 许多肿瘤血管靶向药物也随之 …

[HTML][HTML] Effect of hydroxyapatite bioceramics on the growth of osteoblasts and HIF-α/VEGF signal axis in partial hypoxia environment in vitro

Y Liu, Z Gan, F Hu - Technology and Health Care, 2022 - content.iospress.com
BACKGROUND: Hydroxyapatite bioceramic is a kind of bone implant commonly used in oral
clinic treatment. In the early stage of tissue repair, cells will suffer hypoxic due to the …