Obesity and breast cancer: a paradoxical and controversial relationship influenced by menopausal status

L García-Estévez, J Cortés, S Pérez, I Calvo… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most common tumor in women worldwide, and an increasing public
health concern. Knowledge of both protective and negative risk factors is essential for a …

Cancer progress and priorities: breast cancer

SC Houghton, SE Hankinson - Cancer epidemiology, biomarkers & …, 2021 - AACR
Breast cancer is the most commonly diagnosed invasive cancer among women both
globally and within the United States and the number one cause of cancer-related deaths …

Relationship of established risk factors with breast cancer subtypes

AM McCarthy, T Friebel‐Klingner, S Ehsan… - Cancer …, 2021 - Wiley Online Library
Background Breast cancer is a heterogeneous disease, divided into subtypes based on the
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

Molecular links between central obesity and breast cancer

AA Zimta, AB Tigu, M Muntean, D Cenariu… - International journal of …, 2019 - mdpi.com
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

[HTML][HTML] Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses

S Taurin, H Alkhalifa - Neoplasia, 2020 - Elsevier
The cellular heterogeneity of breast cancers still represents a major therapeutic challenge.
The latest genomic studies have classified breast cancers in distinct clusters to inform the …

Breast cancer population attributable risk proportions associated with body mass index and breast density by race/ethnicity and menopausal status

MCS Bissell, K Kerlikowske, BL Sprague, JA Tice… - … Biomarkers & Prevention, 2020 - AACR
Background: Overweight/obesity and dense breasts are strong breast cancer risk factors
whose prevalences vary by race/ethnicity. The breast cancer population attributable risk …

Updates on triple-negative breast cancer in type 2 diabetes mellitus patients: from risk factors to diagnosis, biomarkers and therapy

S Matou-Nasri, M Aldawood, F Alanazi, AL Khan - Diagnostics, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is usually the most malignant and aggressive
mammary epithelial tumor characterized by the lack of expression for estrogen receptors …

Association of the interaction between mammographic breast density, body mass index, and menopausal status with breast cancer risk among Korean women

TXM Tran, SG Moon, S Kim, B Park - JAMA Network Open, 2021 - jamanetwork.com
Importance Evidence suggests that breast density and body mass index (BMI) are strong
breast cancer risk factors; however, their interactive associations are unknown. Elucidation …

Sedentary behavior and alcohol consumption increase breast cancer risk regardless of menopausal status: a case-control study

JCM Godinho-Mota, LV Gonçalves, JF Mota… - Nutrients, 2019 - mdpi.com
Identification of modifiable risk factors for breast cancer is critical for primary prevention of
the disease. The aim of this study was to evaluate how certain lifestyle variables modify the …

Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano [3, 4-b] pyrazine BAM15

ERM Zunica, CL Axelrod, E Cho, G Spielmann… - Cancer & …, 2021 - Springer
Background Enhanced metabolic plasticity and diversification of energy production is a
hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy …