Osteogenesis imperfecta (OI) is an inherited skeletal dysplasia characterized by bone
fragility and skeletal deformities. While the majority of cases are associated with pathogenic …

Presbycusis is the most common cause of hearing loss in aged subjects, reducing
individual's communicative skills. Age related hearing loss can be defined as a progressive …

The efficacy of romosozumab for severe osteoporosis is uncertain in patients with
osteogenesis imperfecta (OI). This report introduced a severe osteoporotic case of OI to …

Mutations in CRTAP (coding for cartilage-associated protein), LEPRE1 (coding for prolyl 3-
hydroxylase 1 [P3H1]) or PPIB (coding for Cyclophilin B [CYPB]) cause recessive forms of …

Purpose: To identify the characteristic corneal biomechanical properties of osteogenesis
imperfecta (OI), and to compare the corneal biomechanical properties between OI and …

A novel, biocompatible, calcium-based coordination polymer was hydrothermally
synthesized using as linker the bone antiresorptive bisphosphonate alendronate. Its …

Background Total knee arthroplasty (TKA) in patients with skeletal dysplasias is particularly
challenging as a result of the anatomic variances and substantial bony deformities. Little has …

Background: Osteogenesis imperfecta (OI) is a genetic disorder commonly associated with
osteopenia, osteoporosis, bone fractures, bone deformities, and other clinical features. A …

Background: Osteogenesis imperfecta (OI) is a genetic disorder characterized by brittle
bones and long bone deformity. Realignment and intramedullary rodding with telescopic …

Cellular therapy has gained an increasing popularity in recent years. Mesenchymal stem
cells (MSCs) have the potential to differentiate into bone, cartilage, or fat tissue. In recent …