The role of galanin as a multi-functional neuropeptide in the nervous system
D Wynick, SWN Thompson, SB McMahon - Current opinion in …, 2001 - Elsevier
The neuropeptide galanin is expressed developmentally in the DRG and is rapidly up-
regulated 120-fold after peripheral nerve section in the adult. The generation and study of …
regulated 120-fold after peripheral nerve section in the adult. The generation and study of …
Galanin attenuates β-amyloid (Aβ) toxicity in rat cholinergic basal forebrain neurons
X Ding, D MacTavish, S Kar, JH Jhamandas - Neurobiology of disease, 2006 - Elsevier
In brains of Alzheimer's disease (AD) patients, expression of the neuropeptide galanin is
significantly upregulated and galanin-immunoreactive fibers hypertrophy and …
significantly upregulated and galanin-immunoreactive fibers hypertrophy and …
Learning and memory performance in mice lacking the GAL‐R1 subtype of galanin receptor
The neuropeptide galanin induces performance deficits in a wide range of cognitive tasks in
rodents. Three G‐protein‐coupled galanin receptor subtypes, designated GAL‐R1, GAL‐R2 …
rodents. Three G‐protein‐coupled galanin receptor subtypes, designated GAL‐R1, GAL‐R2 …
Neuropeptide alterations in the hippocampal formation and cortex of transgenic mice overexpressing β-amyloid precursor protein (APP) with the Swedish double …
M Diez, S Danner, P Frey, B Sommer… - Neurobiology of …, 2003 - Elsevier
The role of neuropeptides and the significance of peptidergic mechanisms in
neurodegenerative diseases are still unclear. In the periphery, nerve injury results in …
neurodegenerative diseases are still unclear. In the periphery, nerve injury results in …
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice
The neuropeptide galanin is expressed in sympathetic nerve terminals that surround islet
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …
cells and inhibits insulin secretion. To explore its role for islet function, we studied mice with …
Subcellular distribution of histamine, GABA and galanin in tuberomamillary neurons in vitro
TK Kukko-Lukjanov, P Panula - Journal of chemical neuroanatomy, 2003 - Elsevier
Histamine acts as a neurotransmitter in the brain and regulates eg sleep, hibernation,
vigilance, and release of several other transmitters. All histaminergic neurons are found in …
vigilance, and release of several other transmitters. All histaminergic neurons are found in …
Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin
M Kokaia, K Holmberg… - Proceedings of the …, 2001 - National Acad Sciences
The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and
hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We …
hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We …
[HTML][HTML] Physiological roles of group X-secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function
H Sato, Y Isogai, S Masuda, Y Taketomi, Y Miki… - Journal of Biological …, 2011 - ASBMB
Although the secreted phospholipase A 2 (sPLA 2) family has been generally thought to
participate in pathologic events such as inflammation and atherosclerosis, relatively high …
participate in pathologic events such as inflammation and atherosclerosis, relatively high …
Cholinergic deficits and galaninergic hyperinnervation of the nucleus basalis of Meynert in Alzheimer's disease and Lewy body disorders
Aims Galanin is a highly inducible neuroprotective neuropeptide and in Alzheimer's disease
(AD), a network of galaninergic fibres has been reported to hypertrophy and hyperinnervate …
(AD), a network of galaninergic fibres has been reported to hypertrophy and hyperinnervate …
Neuroprotective role for galanin in Alzheimer's disease
Galanin (GAL) and GAL receptors (GALR) are overexpressed in degenerating brain regions
associated with cognitive decline in Alzheimer's disease (AD). The functional consequences …
associated with cognitive decline in Alzheimer's disease (AD). The functional consequences …