Mesenchymal stem cell perspective: cell biology to clinical progress
MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
Cardiomyocyte regeneration: a consensus statement
Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges
L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …
function and reduces scar. These effects occur via stimulation of endogenous repair …
Key transcription factors in the differentiation of mesenchymal stem cells
SG Almalki, DK Agrawal - Differentiation, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells that represent a promising source for
regenerative medicine. MSCs are capable of osteogenic, chondrogenic, adipogenic and …
regenerative medicine. MSCs are capable of osteogenic, chondrogenic, adipogenic and …
Paracrine mechanisms of mesenchymal stem cells in tissue repair
M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives
Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic …
Context Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic
cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; …
cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; …
A Phase II study of autologous mesenchymal stromal cells and c‐kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN …
Aims CONCERT‐HF is an NHLBI‐sponsored, double‐blind, placebo‐controlled, Phase II
trial designed to determine whether treatment with autologous bone marrow‐derived …
trial designed to determine whether treatment with autologous bone marrow‐derived …
MiRNA‐sequence indicates that mesenchymal stem cells and exosomes have similar mechanism to enhance cardiac repair
L Shao, Y Zhang, B Lan, J Wang… - BioMed research …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) repair infarcted heart through paracrine mechanism. We
sought to compare the effectiveness of MSCs and MSC‐derived exosomes (MSC‐Exo) in …
sought to compare the effectiveness of MSCs and MSC‐derived exosomes (MSC‐Exo) in …
Use of mesenchymal stem cells for therapy of cardiac disease
V Karantalis, JM Hare - Circulation research, 2015 - Am Heart Assoc
Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …
remains the leading cause of death in America. The past 15 years has witnessed major …