Although frequently unrecognized, left atrium (LA) function plays a key role in global cardiac
performance as it modulates left ventricle (LV) filling through three main functions: the LA …

Abstract SGLT2 inhibitors (SGLT2i) showed pronounced beneficial effects in patients with
heart failure but the underlying mechanisms remain unclear. We evaluated the effect of …

There is limited data on whether diastolic dysfunction in patients with heart failure (HF) and
recovered ejection fraction (HFrecEF) is associated with worse prognosis. We …

Clinical observations and experimental studies have determined that systemic acid-base
disturbances can profoundly affect the heart. A wealth of information is available on the …

Background Right ventricular (RV) diastolic dysfunction may be prognostic in pulmonary
hypertension (PH). However, its assessment is complex and relies on conductance …

Simple Summary Traditional echocardiographic imaging mainly identifies cardiac diseases
when symptoms are clear. This makes the innovation of new methods for the prediction and …

Background: Osteoprotegerin (OPG) is a molecule which belongs to the tumor necrosis
factor receptor superfamily. OPG concentration is elevated in patients with left ventricle …

Cardiac diastolic dysfunction is prevalent and is a diagnostic criterion for heart failure with
preserved ejection fraction—a burgeoning global health issue. As gold-standard invasive …

Diastole is the sequence of physiological events that occur in the heart during ventricular
filling and principally depends on myocardial relaxation and chamber stiffness. Abnormal …

Aims Patients with heart failure with preserved ejection fraction (HFpEF) are characterized
by impaired diastolic function. Left ventricular (LV) strain–volume loops (SVL) represent the …