New perspectives on osteogenesis imperfecta
A Forlino, WA Cabral, AM Barnes… - Nature Reviews …, 2011 - nature.com
A new paradigm has emerged for osteogenesis imperfecta as a collagen-related disorder.
The more prevalent autosomal dominant forms of osteogenesis imperfecta are caused by …
The more prevalent autosomal dominant forms of osteogenesis imperfecta are caused by …
Osteogenesis imperfecta
JC Marini, WA Cabral - Genetics of bone biology and skeletal disease, 2018 - Elsevier
Osteogenesis imperfecta is a genetic disorder characterized by low bone mass, decreased
bone strength, increased bone fragility, and shortened stature. Autosomal dominant …
bone strength, increased bone fragility, and shortened stature. Autosomal dominant …
Osteogenesis imperfecta in children and adolescents—new developments in diagnosis and treatment
P Trejo, F Rauch - Osteoporosis International, 2016 - Springer
Osteogenesis imperfecta (OI) is the most prevalent heritable bone fragility disorder in
children. It has been known for three decades that the majority of individuals with OI have …
children. It has been known for three decades that the majority of individuals with OI have …
The management of osteoporosis in children
This article reviews the manifestations and risk factors associated with osteoporosis in
childhood, the definition of osteoporosis and recommendations for monitoring and …
childhood, the definition of osteoporosis and recommendations for monitoring and …
Expert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children
R Galindo-Zavala, R Bou-Torrent… - Pediatric …, 2020 - Springer
Background Osteoporosis incidence in children is increasing due to the increased survival
rate of patients suffering from chronic diseases and the increased use of drugs that can …
rate of patients suffering from chronic diseases and the increased use of drugs that can …
Risedronate in children with osteogenesis imperfecta: a randomised, double-blind, placebo-controlled trial
Background Children with osteogenesis imperfecta are often treated with intravenous
bisphosphonates. We aimed to assess the safety and efficacy of risedronate, an orally …
bisphosphonates. We aimed to assess the safety and efficacy of risedronate, an orally …
Alendronate for the treatment of pediatric osteogenesis imperfecta: a randomized placebo-controlled study
abstract Context: Information on the use of oral bisphosphonate agents to treat pediatric
osteogenesis imperfecta (OI) is limited. Objective: The objective of the investigation was to …
osteogenesis imperfecta (OI) is limited. Objective: The objective of the investigation was to …
Intravenous bisphosphonate therapy of young children with osteogenesis imperfecta: skeletal findings during follow up throughout the growing years
T Palomo, F Fassier, J Ouellet, A Sato… - Journal of Bone and …, 2015 - academic.oup.com
Cyclical intravenous bisphosphonate therapy is widely used to treat children with
osteogenesis imperfecta (OI), but little is known about long‐term treatment outcomes. We …
osteogenesis imperfecta (OI), but little is known about long‐term treatment outcomes. We …
Current and emerging treatments for the management of osteogenesis imperfecta
E Monti, M Mottes, P Fraschini, PC Brunelli… - … and clinical risk …, 2010 - Taylor & Francis
Osteogenesis imperfecta (OI) is the most common bone genetic disorder and it is
characterized by bone brittleness and various degrees of growth disorder. Clinical severity …
characterized by bone brittleness and various degrees of growth disorder. Clinical severity …
Osteoporosis in children and adolescents: how to treat and monitor?
S Ciancia, W Högler, RJB Sakkers… - European Journal of …, 2023 - Springer
Osteoporosis is a condition of increased bone fragility associated with fractures. Apart from
primary genetic osteoporotic conditions, secondary osteoporosis in children is being …
primary genetic osteoporotic conditions, secondary osteoporosis in children is being …