Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

Drug development is time‐consuming and expensive. Repurposing existing drugs for new
therapies is an attractive solution that accelerates drug development at reduced …

Food-derived bioactive peptides (FBPs) are gaining interest due to their great potential in
agricultural byproduct valorization and high-activity peptide screening. The introduction of …

Abstract Rhizoma Polygonati (huangjing in Chinese, 黄精) is a medicine food homology
herb used as a component of traditional Chinese medicine treating COVID-19 in the current …

Introduction: Drug repurposing provides a cost-effective strategy to re-use approved drugs
for new medical indications. Several machine learning (ML) and artificial intelligence (AI) …

With the recent explosion in the size of libraries available for screening, virtual screening is
positioned to assume a more prominent role in early drug discovery's search for active …

The virus SARS CoV-2, which causes the respiratory infection COVID-19, continues its
spread across the world and to date has caused more than a million deaths. Although …

Ethnopharmacological relevance Danshen, the dried rhizome of Salvia miltiorrhiza Bge., is
widely used to treat cardio-cerebrovascular diseases in China. However, its role in …

Abstract Ethnopharmacological relevance Dendrobium chrysotoxum Lindl, a well-known
traditional Chinese medicinal herb used in the treatment of gastric disease, is distinguished …

Most steps of drug discovery are now routinely supported and accelerated by computer-
aided drug design tools. Among them, structure-based approaches use the three …