Cancer is the second leading cause of death in the US. Current major treatments for cancer
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …

Lung cancer is the leading cause of cancer deaths worldwide, and this makes it an attractive
disease to review and possibly improve therapeutic treatment options. Surgery, radiation …

Although most activating mutations of epidermal growth factor receptor (EGFR)-mutant non–
small cell lung cancers (NSCLCs) are sensitive to available EGFR tyrosine kinase inhibitors …

Abstract Machine learning (ML) is being ubiquitously incorporated into everyday products
such as Internet search, email spam filters, product recommendations, image classification …

The evolving field of personalised medicine is playing an increasingly important role in
cancer prevention, diagnosis, prognosis and therapeutics. Its importance in clinical …

Triple-negative breast cancer (TNBC) is one of the most aggressive and metastatic breast
cancer subtypes lacking targeted therapy. Our recent work demonstrated that circulating …

Purpose: Ganetespib is a novel inhibitor of the heat shock protein 90 (Hsp90), a chaperone
protein critical to tumor growth and proliferation. In this phase II study, we evaluated the …

Nicotinamide (NAM) is a water-soluble form of Vitamin B3 (niacin) and a precursor of
nicotinamide-adenine dinucleotide (NAD+) which regulates cellular energy metabolism …

Non-small cell lung cancer (NSCLC) is a prominent subtype of lung carcinoma that accounts
for the majority of cancer-related deaths globally, and it is responsible for about 80% to 85 …

Epidermal growth factor receptor (EGFR) inhibitors were among the first type of targeted
agents discovered in cancer and currently constitute the standard of care for a wide range of …