Epilepsy is one of the most common brain disorders that not only causes death worldwide,
but also affects the daily lives of patients. Previous studies have revealed that inflammation …

Microglia, the main resident immune cells in the central nervous system, are implicated in
the pathogenesis of various neurological disorders. Much of our knowledge on microglial …

Introduction Alcohol consumption can induce a neuroinflammatory response and contribute
to the progression of neurodegeneration. However, its association with Parkinson's disease …

Data on the course of viral infections revealed severe inflammation as a consequence of
antiviral immune response. Despite extensive research, there are insufficient data on the …

Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and multiple system atrophy
(MSA) are major neurodegenerative disorders; they are synucleinopathies, whose …

Post-translational modifications (PTMs) of alpha-synuclein (α-syn) can alter protein
aggregation propensity to affect α-syn oligomer and fibril formation. The inflammatory …

Inflammasome biology has been implicated in several diseases that exhibit underlying
inflammatory processes. Neurodegenerative diseases like Alzheimer's disease, Parkinson's …

Parkinson's disease (PD) is a common age-related neurodegenerative disorder
characterized by the aggregation of alpha-synuclein (alphaSYN) building up intraneuronal …

Aging is characterized by progressive degeneration of tissues and organs, and it is
positively associated with an increased mortality rate. The brain, as one of the most …

Despite advances in biomedicine, therapies that prevent neuronal loss have not been
effective. Several strategies targeting the defining markers of the main neurodegenerative …