Introduction: Early dry powder inhalers (DPIs) were designed for low drug doses in asthma
and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked …

The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …

Prediction of the air-particle dynamics in human lungs can reveal critical deposition sites of
toxins or can determine best physical parameters for direct drug delivery and associated …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …

Delivery of therapeutic agents via the pulmonary route has gained significant attention over
the past few decades because this route of administration offers multiple advantages over …

With rapid advances in micro-fabrication processes and the availability of biologically-
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …

Malignant nodules may be due to primary tumors or a metastasis and, given the importance
of diagnosing early primary lung tumors, the detection of pulmonary nodules is critical …

Timely and accurate assessment and diagnosis are extremely important and beneficial for
all diseases, especially for some of the major human disease, such as cancers …

Introduction Drugs for the treatment of respiratory diseases are commonly administered by
oral inhalation. Yet surprisingly little is known about the pulmonary pharmacokinetics of …

Background Volume-controlled ventilation has been suggested to optimize lung deposition
during nebulization although promoting spontaneous ventilation is targeted to avoid …