A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Contemporary genetic research has provided evidences that angioedema represents a
diverse family of disorders related to kinin metabolism, with a much greater genetic …

Hereditary angioedema (HAE), a rare but life-threatening condition, manifests as acute
attacks of facial, laryngeal, genital, or peripheral swelling or abdominal pain secondary to …

BACKGROUND: Hereditary angioedema caused by C1 esterase inhibitor deficiency is a
rare disorder. OBJECTIVE: To compare the efficacy of pasteurized C1 esterase inhibitor …

Excessive retinal vascular permeability contributes to the pathogenesis of proliferative
diabetic retinopathy and diabetic macular edema, leading causes of vision loss in working …

Background Hereditary angio‐oedema (HAE) is a rare disease caused by deficiency of
complement C1 inhibitor (C1 inhibitor). The diagnosis is challenging as the disease can …

Primary defence against invading microorganisms depends on a functional innate immune
system and the complement system plays a major role in such immunity. Deficiencies in one …

Background Angiotensin-converting enzyme (ACE) inhibitors are associated with
angioedema episodes that are potentially life-threatening. Few data are available on the …

These parameters were developed by the Joint Task Force on Practice Parameters (JTFPP),
representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the …

OBJECTIVE: The course of hereditary angioedema (HAE) and the efficacy and safety of
human C1-INH concentrate were appraised during pregnancy and the postpartum period, in …