Exosomal noncoding RNAs: key players in glioblastoma drug resistance

A Movahedpour, SH Khatami, M Khorsand… - Molecular and Cellular …, 2021 - Springer
Glioma, as one of the most severe human malignancies, is defined as the Central Nervous
System's (CNS) tumors. Glioblastoma (GBM) in this regard, is the most malignant type of …

H19 promotes non‐small‐cell lung cancer (NSCLC) development through STAT3 signaling via sponging miR‐17

Z Huang, W Lei, HB Hu, H Zhang… - Journal of cellular …, 2018 - Wiley Online Library
LncRNAs can exhibit crucial roles in the development of multiple cancers, including non‐
small cell lung cancer (NSCLC). Currently, we investigated the role of lncRNA H19 in …

MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours

AL Leichter, MJ Sullivan, MR Eccles, A Chatterjee - Molecular cancer, 2017 - Springer
The development of childhood solid tumours is tied to early developmental processes.
These tumours may be complex and heterogeneous, and elucidating the aberrant …

The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

The role of non-coding RNAs in glioma

A Goenka, DM Tiek, X Song, RP Iglesia, M Lu, B Hu… - Biomedicines, 2022 - mdpi.com
For decades, research in cancer biology has been focused on the protein-coding fraction of
the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has …

MicroRNAs regulate cell cycle and cell death pathways in glioblastoma

ISEE Sati, I Parhar - International journal of molecular sciences, 2021 - mdpi.com
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its
resistance to the current treatment regimen. Over the last few decades, a significant amount …

Ketogenic diet in the treatment of gliomas and glioblastomas

S Dal Bello, F Valdemarin, D Martinuzzi, F Filippi… - Nutrients, 2022 - mdpi.com
In recent years, scientific interest in the use of the ketogenic diet (KD) as a complementary
approach to the standard cancer therapy has grown, in particular against those of the central …

miR-205: a potential biomedicine for cancer therapy

N Chauhan, A Dhasmana, M Jaggi, SC Chauhan… - Cells, 2020 - mdpi.com
microRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of
their target mRNAs post transcriptionally. miRNAs are known to regulate not just a gene but …

Breaching barriers in glioblastoma. Part I: Molecular pathways and novel treatment approaches

A Miranda, M Blanco-Prieto, J Sousa, A Pais… - International journal of …, 2017 - Elsevier
Glioblastoma multiforme (GBM) is the most common primary brain tumour, and the most
aggressive in nature. The prognosis for patients with GBM remains poor, with a median …

LncRNA H19 promotes cell proliferation, migration, and angiogenesis of glioma by regulating Wnt5a/β-catenin pathway via targeting miR-342

Q Zhou, ZZ Liu, H Wu, WL Kuang - Cellular and molecular neurobiology, 2022 - Springer
Glioma is the most common malignant brain tumor and long non-coding RNAs (lncRNAs)
have been reported to play an important role in the growth and angiogenesis of glioma …