[HTML][HTML] Glioblastoma: new therapeutic strategies to address cellular and genomic complexity
X Cai, ME Sughrue - Oncotarget, 2018 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is the most invasive and devastating primary brain tumor with a median
overall survival rate about 18 months with aggressive multimodality therapy. Its unique …
overall survival rate about 18 months with aggressive multimodality therapy. Its unique …
[HTML][HTML] LncRNA DGCR5 plays a tumor-suppressive role in glioma via the miR-21/Smad7 and miR-23a/PTEN axes
Z He, J Long, C Yang, B Gong, M Cheng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Glioma is one of the most commonly diagnosed brain malignancies with a high cancer-
related death rate in humans. The prognosis of glioma patients is still unsatisfactory. In the …
related death rate in humans. The prognosis of glioma patients is still unsatisfactory. In the …
[HTML][HTML] The role of microRNAs in multidrug resistance of glioblastoma
Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
HMGB3 promotes the proliferation and metastasis of glioblastoma and is negatively regulated by miR‐200b‐3p and miR‐200c‐3p
J Liu, L Wang, X Li - Cell Biochemistry and Function, 2018 - Wiley Online Library
High mobility group box 3 (HMGB3) is strongly involved in oncogenesis in a variety of
cancers. In the present study, we have explored the role of HMGB3 in glioblastoma …
cancers. In the present study, we have explored the role of HMGB3 in glioblastoma …
[HTML][HTML] miR-874 regulates multiple-drug resistance in gastric cancer by targeting ATG16L1
H Huang, J Tang, L Zhang, Y Bu… - … Journal of Oncology, 2018 - spandidos-publications.com
Chemotherapy is an important treatment option for gastric cancer (GC); however,
chemotherapy usually fails due to drug resistance, particularly multidrug resistance (MDR) …
chemotherapy usually fails due to drug resistance, particularly multidrug resistance (MDR) …
[HTML][HTML] Serum microRNA profiling in patients with glioblastoma: a survival analysis
Because circulating microRNAs (miRNAs) have drawn a great deal of attention as promising
novel cancer diagnostics and prognostic biomarkers, we sought to identify serum miRNAs …
novel cancer diagnostics and prognostic biomarkers, we sought to identify serum miRNAs …
MicroRNA-based drugs for brain tumors
S Anthiya, A Griveau, C Loussouarn, P Baril, M Garnett… - Trends in cancer, 2018 - cell.com
MicroRNAs (miRNAs) are key regulatory elements encoded by the genome. A single miRNA
can downregulate the expression of multiple genes involved in diverse functions. Because …
can downregulate the expression of multiple genes involved in diverse functions. Because …
[HTML][HTML] A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models
N Sadeghipour, SU Kumar, TF Massoud… - Scientific Reports, 2022 - nature.com
Glioblastoma (GBM) is the most common malignant brain tumor. Available treatments have
limited success because most patients develop chemoresistance. Alternative strategies are …
limited success because most patients develop chemoresistance. Alternative strategies are …
[HTML][HTML] Therapeutically significant microRNAs in primary and metastatic brain malignancies
Simple Summary The overall survival of brain cancer patients remains grim, with
conventional therapies such as chemotherapy and radiotherapy only providing marginal …
conventional therapies such as chemotherapy and radiotherapy only providing marginal …
[HTML][HTML] The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells
S Brodie, HK Lee, W Jiang, S Cazacu, C Xiang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Despite advances in novel therapeutic approaches for the treatment of glioblastoma (GBM),
the median survival of 12-14 months has not changed significantly. Therefore, there is an …
the median survival of 12-14 months has not changed significantly. Therefore, there is an …