Noncoding RNAs in glioblastoma: emerging biological concepts and potential therapeutic implications
Simple Summary Since the completion of the Human Genome Project, noncoding RNAs
(ncRNAs) have emerged as an important class of genetic regulators. Several classes of …
(ncRNAs) have emerged as an important class of genetic regulators. Several classes of …
Targeting human brain cancer stem cells by curcumin-loaded nanoparticles grafted with anti-aldehyde dehydrogenase and sialic acid: Colocalization of ALDH and …
The use of chemotherapy against brain tumors faces various limitations to achieving its
therapeutic effect, due to both the inability of anticancer agents to cross the blood–brain …
therapeutic effect, due to both the inability of anticancer agents to cross the blood–brain …
Allicin induces apoptosis through activation of both intrinsic and extrinsic pathways in glioma cells
C Li, H Jing, G Ma, P Liang - Molecular medicine …, 2018 - spandidos-publications.com
Allicin is an extract purified from Allium sativum (garlic), and previous research has indicated
that Allicin has an inhibitory effect on many kinds of tumor cells. The aim of the present study …
that Allicin has an inhibitory effect on many kinds of tumor cells. The aim of the present study …
Identification of a novel role of IL-13Rα2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway
Background Previously, we have demonstrated that Interleukin 13 receptor alpha 2 (IL-
13Rα2) is overexpressed in approximate 78% Glioblastoma multiforme (GBM) samples. We …
13Rα2) is overexpressed in approximate 78% Glioblastoma multiforme (GBM) samples. We …
Molecular and cellular complexity of glioma. Focus on tumour microenvironment and the use of molecular and imaging biomarkers to overcome treatment resistance
S Valtorta, D Salvatore, P Rainone, S Belloli… - International Journal of …, 2020 - mdpi.com
This review highlights the importance and the complexity of tumour biology and
microenvironment in the progression and therapy resistance of glioma. Specific gene …
microenvironment in the progression and therapy resistance of glioma. Specific gene …
IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway
KC Chen, PH Chen, KH Ho, CM Shih, CM Chou… - PLoS …, 2019 - journals.plos.org
Temozolomide (TMZ) is a first-line alkylating agent for glioblastoma multiforme (GBM).
Clarifying the mechanisms inducing TMZ insensitivity may be helpful in improving its …
Clarifying the mechanisms inducing TMZ insensitivity may be helpful in improving its …
Sequencing and Bioinformatics analysis of lncRNA/circRNA-miRNA-mRNA in Glioblastoma multiforme
R Wang, Q Li, X Chu, N Li, H Liang, F He - Metabolic Brain Disease, 2023 - Springer
Evidence suggests that non-coding RNAs have a role in glioblastoma multiforme (GBM),
although the regulatory mechanisms controlled by competing endogenous RNAs (ceRNAs) …
although the regulatory mechanisms controlled by competing endogenous RNAs (ceRNAs) …
Friend or foe: Paradoxical roles of autophagy in gliomagenesis
DCR Batara, MC Choi, HU Shin, H Kim, SH Kim - Cells, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain
tumor in adults, with a poor median survival of approximately 15 months after diagnosis …
tumor in adults, with a poor median survival of approximately 15 months after diagnosis …
microRNA-181a mediates the chemo-sensitivity of glioblastoma to carmustine and regulates cell proliferation, migration, and apoptosis
Glioblastoma multiform (GBM) as the most frequent and lethal brain tumor is defined by
aggressive invasiveness and considerable resistance to chemotherapy. The molecular …
aggressive invasiveness and considerable resistance to chemotherapy. The molecular …
Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species
A Nakaoka, M Nakahana, S Inubushi… - Oncology …, 2021 - spandidos-publications.com
The precise mechanism of intercellular communication between cancer cells following
radiation exposure is unclear. Exosomes are membrane‑enclosed small vesicles comprising …
radiation exposure is unclear. Exosomes are membrane‑enclosed small vesicles comprising …