Insights into the roles of non-coding RNAs and angiogenesis in glioblastoma: An overview of current research and future perspectives

Z Song, Z Xue, Y Wang, M Imran, M Assiri… - Biochimica et Biophysica …, 2024 - Elsevier
Glioblastoma (GBM) is a highly aggressive type of primary brain cancer with a poor
prognosis, and despite intensive research, survival rates have not significantly improved …

MiR-148a inhibits the proliferation and migration of glioblastoma by targeting ITGA9

TJ Xu, P Qiu, YB Zhang, SY Yu, GM Xu, W Yang - Human cell, 2019 - Springer
Glioblastoma is a common malignant primary intracranial tumor characterized by rapid
invasive growth and a high recurrence rate after surgery. MicroRNAs (miRNAs) are involved …

[HTML][HTML] miRNA in molecular diagnostics

M Matulić, P Gršković, A Petrović, V Begić, S Harabajsa… - Bioengineering, 2022 - mdpi.com
MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …

[HTML][HTML] Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions

D Thuringer, J Boucher, G Jego, N Pernet, L Cronier… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Extensive invasion and angiogenesis are hallmark features of malignant glioblastomas.
Here, we co-cultured U87 human glioblastoma cells and human microvascular endothelial …

[HTML][HTML] The inhibition of microRNA-128 on IGF-1-activating mTOR signaling involves in temozolomide-induced glioma cell apoptotic death

PH Chen, CH Cheng, CM Shih, KH Ho, CW Lin… - PloS one, 2016 - journals.plos.org
Temozolomide (TMZ), an alkylating agent of the imidazotetrazine series, is a first-line
chemotherapeutic drug used in the clinical therapy of glioblastoma multiforme, the most …

[HTML][HTML] Recent development in NKT-based immunotherapy of glioblastoma: From bench to bedside

Y Li, A Sharma, J Maciaczyk… - International Journal of …, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is an aggressive and dismal disease with a median overall
survival of around 15 months and a 5-year survival rate of 7.2%. Owing to genetic mutations …

The effect of miR‐579 on the PI3K/AKT pathway in human glioblastoma PTEN mutant cell lines

MR Kalhori, S Irani, M Soleimani… - Journal of cellular …, 2019 - Wiley Online Library
Glioblastoma multiform (GBM) is a type of aggressive brain cancer with limited success in
standard treatment. MicroRNAs are one of the most beneficial tools for diagnosis, prognosis …

[HTML][HTML] MicroRNA-214 targets PTK6 to inhibit tumorigenic potential and increase drug sensitivity of prostate cancer cells

P Cagle, S Niture, A Srivastava, M Ramalinga… - Scientific reports, 2019 - nature.com
Prostate cancer is the most commonly diagnosed cancer in men with African American men
disproportionally suffering from the burden of this disease. Biomarkers that could …

[HTML][HTML] Role of endolysosomes and inter-organellar signaling in brain disease

Z Afghah, X Chen, JD Geiger - Neurobiology of disease, 2020 - Elsevier
Endosomes and lysosomes (endolysosomes) are membrane bounded organelles that play
a key role in cell survival and cell death. These acidic intracellular organelles are the …

[HTML][HTML] A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and …

Q Zhou, M Shaya, Y Kugeluke, Q Fu, S Li… - BMC neuroscience, 2022 - Springer
Background Glioblastoma (GBM) is an aggressive and malignant brain tumor with extremely
poor prognosis. Despite advances in treatment, the pathogenesis of GBM remains elusive …