[HTML][HTML] Brain phosphorylation of MeCP2 at serine 164 is developmentally regulated and globally alters its chromatin association

G Stefanelli, A Gandaglia, M Costa, MS Cheema… - Scientific reports, 2016 - nature.com
MeCP2 is a transcriptional regulator whose functional alterations are responsible for several
autism spectrum and mental disorders. Post-translational modifications (PTMs) and …

Potential role of microRNAs as biomarkers in human glioblastoma: A mini systematic review from 2015 to 2020

MR de Menezes, MEA Acioli, ACL da Trindade… - Molecular Biology …, 2021 - Springer
Glioblastoma (GBM) is the most common, aggressive and malignant type of glioma, with
poor prognosis, despite advances in medical knowledge and technology. It's known that …

Nano-immunotherapeutic strategies for targeted RNA delivery: Emphasizing the role of monocyte/macrophages as nanovehicles to treat glioblastoma multiforme

ALE Manicum, S Sargazi, S Razzaq, GV Kumar… - Journal of Drug Delivery …, 2022 - Elsevier
Glioblastoma multiforme (GBM) is considered the most aggressive and heterogeneous type
of brain malignancy. The substantial invasion of the central nervous system parenchyma is a …

MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma

J Sakata, T Sasayama, K Tanaka, H Nagashima… - Journal of Neuro …, 2019 - Springer
Background MicroRNAs (miRs) regulate many biological processes, such as invasion,
angiogenesis, and metastasis. Glioblastoma (GBM) patients with metastasis/metastatic …

Glycolytic inhibitor 2-Deoxy-d-Glucose activates migration and invasion in glioblastoma cells through modulation of the miR-7-5p/TFF3 signaling pathway

A Shukla, P Gupta, R Singh, DP Mishra - Biochemical and biophysical …, 2018 - Elsevier
Glioblastomas (GBMs) are characterized by the metabolic shift towards aerobic glycolysis,
rapid proliferation and acquisition of the migratory and invasive phenotype aiding tumor …

Glioma cell secretion: a driver of tumor progression and a potential therapeutic target

DA Almiron Bonnin, MC Havrda, MA Israel - Cancer research, 2018 - AACR
Cellular secretion is an important mediator of cancer progression. Secreted molecules in
glioma are key components of complex autocrine and paracrine pathways that mediate …

[HTML][HTML] Lentiviral vectors as tools for the study and treatment of glioblastoma

C Del Vecchio, A Calistri, C Parolin… - Cancers, 2019 - mdpi.com
Glioblastoma (GBM) has the worst prognosis among brain tumors, hence basic biology,
preclinical, and clinical studies are necessary to design effective strategies to defeat this …

microRNA as a systemic intervention in the specific breast cancer subtypes with C‐MYC impacts; introducing subtype‐based appraisal tool

V Pourteimoor, M Paryan… - Journal of cellular …, 2018 - Wiley Online Library
Breast cancer is indisputably a heterogeneous disease, in which a formidable combination
of definitely dis‐regulated C‐MYC and microRNA (miRNA) profiles along with other factors …

miR-17-5p-CXCL14 axis related transcriptome profile and clinical outcome in diffuse gliomas

A Zeng, J Yin, Z Wang, C Zhang, R Li, Z Zhang… - …, 2018 - Taylor & Francis
ABSTRACT GBM tissues are comprised of not only tumor cells but also tumor-associated
nontumor cells, such as stromal cells and immune cells, which dilute the purity of glioma …

miR-720 is a key regulator of glioma migration and invasion by controlling TARSL2 expression

Y Liu, K Jiang, T Zhi, X Xu - Human Cell, 2021 - Springer
Glioblastoma (GBM) is the most lethal type of primary brain tumor and is characterized by
diffuse infiltrative growth. However, the mechanisms that control this phenotype remain …