A model of dysregulated crosstalk between dendritic, natural killer, and regulatory T cells in chronic obstructive pulmonary disease

DT Mengistu, JL Curtis, CM Freeman - Trends in Immunology, 2024 - cell.com
Chronic obstructive pulmonary disease (COPD) is characterized by infiltration of the airways
and lung parenchyma by inflammatory cells. Lung pathology results from the cumulative …

scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory system

K Chen, Y Han, Y Wang, D Zhou, F Wu, W Cai… - Iscience, 2024 - cell.com
The human respiratory system is a complex and important system that can suffer a variety of
diseases. Single-cell sequencing technologies, applied in many respiratory disease studies …

Computational Deconvolution of Cell Type-Specific Gene Expression in COPD and IPF Lungs Reveals Disease Severity Associations

MH Ryu, JH Yun, K Kim, M Gentili, A Ghosh, F Sciurba… - medRxiv, 2024 - medrxiv.org
Rationale Chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis
(IPF) are debilitating diseases associated with divergent histopathological changes in the …