Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …

Gene identity by descent (IBD) is a fundamental concept that underlies genetically mediated
similarities among relatives. Gene IBD is traced through ancestral meioses and is defined …

Non-communicable diseases, including cancer, are overtaking infectious disease as the
leading health-care threat in middle-income and low-income countries. Latin American and …

Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …

The large and diverse population of Latin America is potentially a powerful resource for
elucidating the genetic basis of complex traits through admixture mapping. However, no …

Abstract Background Latin America, China and India are experiencing unprecedentedly
rapid demographic ageing with an increasing number of people with dementia. The 10/66 …

Over the past 15 years, more than 2,000 quantitative trait loci (QTLs) have been identified in
crosses between inbred strains of mice and rats, but less than 1% have been characterized …

Existing methods to ascertain small sets of markers for the identification of human population
structure require prior knowledge of individual ancestry. Based on Principal Components …

Obesity rates have escalated to the point of a global pandemic with varying prevalence
across ethnic groups. These differences are partially explained by lifestyle factors in addition …

This paper presents an ethnographic case study of the use of race in two interconnected
laboratories of medical genetics. Specifically, it examines how researchers committed to …